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Page 1
Single-molecule chromatin configurations link transcription factor binding to expression in human cells.
Doughty BR, Hinks MM, Schaepe JM, Marinov GK, Thurm AR, Rios-Martinez C, Parks BE, Tan Y, Marklund E, Dubocanin D, Bintu L, Greenleaf WJ. Doughty BR, et al. Among authors: hinks mm. bioRxiv [Preprint]. 2024 Feb 4:2024.02.02.578660. doi: 10.1101/2024.02.02.578660. bioRxiv. 2024. Update in: Nature. 2024 Dec;636(8043):745-754. doi: 10.1038/s41586-024-08219-w PMID: 38352517 Free PMC article. Updated. Preprint.
Single-cell chromatin state transitions during epigenetic memory formation.
Fujimori T, Rios-Martinez C, Thurm AR, Hinks MM, Doughty BR, Sinha J, Le D, Hafner A, Greenleaf WJ, Boettiger AN, Bintu L. Fujimori T, et al. Among authors: hinks mm. bioRxiv [Preprint]. 2023 Oct 5:2023.10.03.560616. doi: 10.1101/2023.10.03.560616. bioRxiv. 2023. PMID: 37873344 Free PMC article. Preprint.
The H3.3 K36M oncohistone disrupts the establishment of epigenetic memory through loss of DNA methylation.
Sinha J, Nickels JF, Thurm AR, Ludwig CH, Archibald BN, Hinks MM, Wan J, Fang D, Bintu L. Sinha J, et al. Among authors: hinks mm. bioRxiv [Preprint]. 2023 Oct 14:2023.10.13.562147. doi: 10.1101/2023.10.13.562147. bioRxiv. 2023. Update in: Mol Cell. 2024 Oct 17;84(20):3899-3915.e7. doi: 10.1016/j.molcel.2024.09.015 PMID: 37873347 Free PMC article. Updated. Preprint.
Single-molecule states link transcription factor binding to gene expression.
Doughty BR, Hinks MM, Schaepe JM, Marinov GK, Thurm AR, Rios-Martinez C, Parks BE, Tan Y, Marklund E, Dubocanin D, Bintu L, Greenleaf WJ. Doughty BR, et al. Among authors: hinks mm. Nature. 2024 Dec;636(8043):745-754. doi: 10.1038/s41586-024-08219-w. Epub 2024 Nov 20. Nature. 2024. PMID: 39567683