Goodchild SJ - Search Results

1

Molecular Pharmacology of Selective Na_V1.6 and Dual Na_V1.6/Na_V1.2 Channel Inhibitors that Suppress Excitatory Neuronal Activity Ex Vivo.

Goodchild SJ, Shuart NG, Williams AD, Ye W, Parrish RR, Soriano M, Thouta S, Mezeyova J, Waldbrook M, Dean R, Focken T, Ghovanloo MR, Ruben PC, Scott F, Cohen CJ, Empfield J, Johnson JP. Goodchild SJ, et al. ACS Chem Neurosci. 2024 Mar 20;15(6):1169-1184. doi: 10.1021/acschemneuro.3c00757. Epub 2024 Feb 15. ACS Chem Neurosci. 2024. PMID: 38359277 Free PMC article.

2

Basis for allosteric open-state stabilization of voltage-gated potassium channels by intracellular cations.

Goodchild SJ, Xu H, Es-Salah-Lamoureux Z, Ahern CA, Fedida D. Goodchild SJ, et al. J Gen Physiol. 2012 Nov;140(5):495-511. doi: 10.1085/jgp.201210823. Epub 2012 Oct 15. J Gen Physiol. 2012. PMID: 23071269 Free PMC article.

3

Sequence of gating charge movement and pore gating in HERG activation and deactivation pathways.

Goodchild SJ, Macdonald LC, Fedida D. Goodchild SJ, et al. Biophys J. 2015 Mar 24;108(6):1435-1447. doi: 10.1016/j.bpj.2015.02.014. Biophys J. 2015. PMID: 25809256 Free PMC article.

4

The neutral, hydrophobic isoleucine at position I521 in the extracellular S4 domain of hERG contributes to channel gating equilibrium.

Dou Y, Goodchild SJ, Velde RV, Wu Y, Fedida D. Dou Y, et al. Among authors: goodchild sj. Am J Physiol Cell Physiol. 2013 Aug 15;305(4):C468-78. doi: 10.1152/ajpcell.00147.2013. Epub 2013 Jun 12. Am J Physiol Cell Physiol. 2013. PMID: 23761630 Free article.

5

Local anesthetic inhibition of a bacterial sodium channel.

Lee S, Goodchild SJ, Ahern CA. Lee S, et al. Among authors: goodchild sj. J Gen Physiol. 2012 Jun;139(6):507-16. doi: 10.1085/jgp.201210779. J Gen Physiol. 2012. PMID: 22641643 Free PMC article.

6

Allosteric block of KCa2 channels by apamin.

Lamy C, Goodchild SJ, Weatherall KL, Jane DE, Liégeois JF, Seutin V, Marrion NV. Lamy C, et al. Among authors: goodchild sj. J Biol Chem. 2010 Aug 27;285(35):27067-27077. doi: 10.1074/jbc.M110.110072. Epub 2010 Jun 18. J Biol Chem. 2010. PMID: 20562108 Free PMC article.

7

Blockade of permeation by potassium but normal gating of the G628S nonconducting hERG channel mutant.

Es-Salah-Lamoureux Z, Xiong PY, Goodchild SJ, Ahern CA, Fedida D. Es-Salah-Lamoureux Z, et al. Among authors: goodchild sj. Biophys J. 2011 Aug 3;101(3):662-70. doi: 10.1016/j.bpj.2011.06.028. Biophys J. 2011. PMID: 21806934 Free PMC article.

8

Inhibition of K(Ca)2.2 and K(Ca)2.3 channel currents by protonation of outer pore histidine residues.

Goodchild SJ, Lamy C, Seutin V, Marrion NV. Goodchild SJ, et al. J Gen Physiol. 2009 Oct;134(4):295-308. doi: 10.1085/jgp.200910252. J Gen Physiol. 2009. PMID: 19786583 Free PMC article.

9

Methadone: does it really have low efficacy at micro-opioid receptors?

Rodriguez-Martin I, Braksator E, Bailey CP, Goodchild S, Marrion NV, Kelly E, Henderson G. Rodriguez-Martin I, et al. Neuroreport. 2008 Mar 26;19(5):589-93. doi: 10.1097/WNR.0b013e3282f97b64. Neuroreport. 2008. PMID: 18388744

10

Small conductance calcium-activated potassium channels: from structure to function.

Weatherall KL, Goodchild SJ, Jane DE, Marrion NV. Weatherall KL, et al. Among authors: goodchild sj. Prog Neurobiol. 2010 Jul;91(3):242-55. doi: 10.1016/j.pneurobio.2010.03.002. Epub 2010 Mar 30. Prog Neurobiol. 2010. PMID: 20359520 Review.

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