Mirkin SM - Search Results

1

Pathogenic CANVAS (AAGGG)n repeats stall DNA replication due to the formation of alternative DNA structures.

Hisey JA, Radchenko EA, Mandel NH, McGinty RJ, Matos-Rodrigues G, Rastokina A, Masnovo C, Ceschi S, Hernandez A, Nussenzweig A, Mirkin SM. Hisey JA, et al. Among authors: mirkin sm. Nucleic Acids Res. 2024 May 8;52(8):4361-4374. doi: 10.1093/nar/gkae124. Nucleic Acids Res. 2024. PMID: 38381906 Free PMC article.

2

Overcoming natural replication barriers: differential helicase requirements.

Anand RP, Shah KA, Niu H, Sung P, Mirkin SM, Freudenreich CH. Anand RP, et al. Among authors: mirkin sm. Nucleic Acids Res. 2012 Feb;40(3):1091-105. doi: 10.1093/nar/gkr836. Epub 2011 Oct 7. Nucleic Acids Res. 2012. PMID: 21984413 Free PMC article.

3

Effects of Friedreich's ataxia GAA repeats on DNA replication in mammalian cells.

Chandok GS, Patel MP, Mirkin SM, Krasilnikova MM. Chandok GS, et al. Among authors: mirkin sm. Nucleic Acids Res. 2012 May;40(9):3964-74. doi: 10.1093/nar/gks021. Epub 2012 Jan 19. Nucleic Acids Res. 2012. PMID: 22262734 Free PMC article.

4

Coupling transcriptional state to large-scale repeat expansions in yeast.

Shah KA, McGinty RJ, Egorova VI, Mirkin SM. Shah KA, et al. Among authors: mirkin sm. Cell Rep. 2014 Dec 11;9(5):1594-1602. doi: 10.1016/j.celrep.2014.10.048. Epub 2014 Nov 20. Cell Rep. 2014. PMID: 25464841 Free PMC article.

5

Transcription blockage by stable H-DNA analogs in vitro.

Pandey S, Ogloblina AM, Belotserkovskii BP, Dolinnaya NG, Yakubovskaya MG, Mirkin SM, Hanawalt PC. Pandey S, et al. Among authors: mirkin sm. Nucleic Acids Res. 2015 Aug 18;43(14):6994-7004. doi: 10.1093/nar/gkv622. Epub 2015 Jun 22. Nucleic Acids Res. 2015. PMID: 26101261 Free PMC article.

6

A Defective mRNA Cleavage and Polyadenylation Complex Facilitates Expansions of Transcribed (GAA)_n Repeats Associated with Friedreich's Ataxia.

McGinty RJ, Puleo F, Aksenova AY, Hisey JA, Shishkin AA, Pearson EL, Wang ET, Housman DE, Moore C, Mirkin SM. McGinty RJ, et al. Among authors: mirkin sm. Cell Rep. 2017 Sep 5;20(10):2490-2500. doi: 10.1016/j.celrep.2017.08.051. Cell Rep. 2017. PMID: 28877480 Free PMC article.

7

Quantitative Analysis of the Rates for Repeat-Mediated Genome Instability in a Yeast Experimental System.

Radchenko EA, McGinty RJ, Aksenova AY, Neil AJ, Mirkin SM. Radchenko EA, et al. Among authors: mirkin sm. Methods Mol Biol. 2018;1672:421-438. doi: 10.1007/978-1-4939-7306-4_29. Methods Mol Biol. 2018. PMID: 29043640 Free PMC article.

8

Nanopore sequencing of complex genomic rearrangements in yeast reveals mechanisms of repeat-mediated double-strand break repair.

McGinty RJ, Rubinstein RG, Neil AJ, Dominska M, Kiktev D, Petes TD, Mirkin SM. McGinty RJ, et al. Among authors: mirkin sm. Genome Res. 2017 Dec;27(12):2072-2082. doi: 10.1101/gr.228148.117. Epub 2017 Nov 7. Genome Res. 2017. PMID: 29113982 Free PMC article.

9

RNA-DNA hybrids promote the expansion of Friedreich's ataxia (GAA)n repeats via break-induced replication.

Neil AJ, Liang MU, Khristich AN, Shah KA, Mirkin SM. Neil AJ, et al. Among authors: mirkin sm. Nucleic Acids Res. 2018 Apr 20;46(7):3487-3497. doi: 10.1093/nar/gky099. Nucleic Acids Res. 2018. PMID: 29447396 Free PMC article.

10

Cis- and Trans-Modifiers of Repeat Expansions: Blending Model Systems with Human Genetics.

McGinty RJ, Mirkin SM. McGinty RJ, et al. Among authors: mirkin sm. Trends Genet. 2018 Jun;34(6):448-465. doi: 10.1016/j.tig.2018.02.005. Epub 2018 Mar 19. Trends Genet. 2018. PMID: 29567336 Free PMC article. Review.

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