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264 results

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Page 1
B cells orchestrate tolerance to the neuromyelitis optica autoantigen AQP4.
Afzali AM, Nirschl L, Sie C, Pfaller M, Ulianov O, Hassler T, Federle C, Petrozziello E, Kalluri SR, Chen HH, Tyystjärvi S, Muschaweckh A, Lammens K, Delbridge C, Büttner A, Steiger K, Seyhan G, Ottersen OP, Öllinger R, Rad R, Jarosch S, Straub A, Mühlbauer A, Grassmann S, Hemmer B, Böttcher JP, Wagner I, Kreutzfeldt M, Merkler D, Pardàs IB, Schmidt Supprian M, Buchholz VR, Heink S, Busch DH, Klein L, Korn T. Afzali AM, et al. Among authors: straub a. Nature. 2024 Mar;627(8003):407-415. doi: 10.1038/s41586-024-07079-8. Epub 2024 Feb 21. Nature. 2024. PMID: 38383779 Free PMC article.
A mass cytometry approach to track the evolution of T cell responses during infection and immunotherapy by paired T cell receptor repertoire and T cell differentiation state analysis.
Castillo JG, DeBarge R, Mende A, Tenvooren I, Marquez DM, Straub A, Busch DH, Spitzer MH, DuPage M. Castillo JG, et al. Among authors: straub a. bioRxiv [Preprint]. 2024 Jan 12:2024.01.11.575237. doi: 10.1101/2024.01.11.575237. bioRxiv. 2024. PMID: 38260336 Free PMC article. Preprint.
Predicting T cell receptor functionality against mutant epitopes.
Drost F, Dorigatti E, Straub A, Hilgendorf P, Wagner KI, Heyer K, López Montes M, Bischl B, Busch DH, Schober K, Schubert B. Drost F, et al. Among authors: straub a. Cell Genom. 2024 Sep 11;4(9):100634. doi: 10.1016/j.xgen.2024.100634. Epub 2024 Aug 15. Cell Genom. 2024. PMID: 39151427 Free PMC article.
Discovery and Preclinical Characterization of Fulacimstat (BAY 1142524), a Potent and Selective Chymase Inhibitor As a New Profibrinolytic Approach for Safe Thrombus Resolution.
Fürstner C, Ackerstaff J, Meier H, Straub A, Mittendorf J, Schamberger J, Schäfer M, Börngen K, Jörißen H, Zubov D, Zimmermann K, Tersteegen A, Geiss V, Hartmann E, Albrecht-Küpper B, D'Orléans-Juste P, Lapointe C, Vincent L, Heitmeier S, Tinel H. Fürstner C, et al. Among authors: straub a. J Med Chem. 2024 Nov 14. doi: 10.1021/acs.jmedchem.4c01819. Online ahead of print. J Med Chem. 2024. PMID: 39541507
Discovery of BAY 2413555, First Selective Positive Allosteric Modulator of the M2 Receptor to Restore Cardiac Autonomic Balance.
Vakalopoulos A, Basting D, Brechmann M, Teller H, Boultadakis Arapinis M, Straub A, Mittendorf J, Meininghaus M, Müller T, Nowak-Reppel K, Schäfer M, Wittwer M, Kullmann M, Terjung C, Lang D, Poethko T, Marquardt T, Freudenberger T, Mondritzki T, Hüser J, Heckmann M, Tinel H. Vakalopoulos A, et al. Among authors: straub a. J Med Chem. 2024 Nov 14;67(21):19165-19187. doi: 10.1021/acs.jmedchem.4c01590. Epub 2024 Oct 28. J Med Chem. 2024. PMID: 39463278
Neuromuscular dysfunction and pathogenesis in triosephosphate isomerase deficiency.
Myers TD, Li Y, Taiclet S, Cabada-Aguirre P, Kuti E, McClure K, Blanchard C, Wolosowicz M, Homanics GE, Straub AC, Meriney SD, Palladino MJ. Myers TD, et al. Among authors: straub ac. Sci Rep. 2024 Aug 10;14(1):18575. doi: 10.1038/s41598-024-69618-7. Sci Rep. 2024. PMID: 39127839 Free PMC article.
264 results