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PCID2 dysregulates transcription and viral RNA processing to promote HIV-1 latency.
Crespo R, Ne E, Reinders J, Meier JIJ, Li C, Jansen S, Górska A, Koçer S, Kan TW, Doff W, Dekkers D, Demmers J, Palstra RJ, Rao S, Mahmoudi T. Crespo R, et al. Among authors: kan tw. iScience. 2024 Feb 6;27(3):109152. doi: 10.1016/j.isci.2024.109152. eCollection 2024 Mar 15. iScience. 2024. PMID: 38384833 Free PMC article.
Gliotoxin, identified from a screen of fungal metabolites, disrupts 7SK snRNP, releases P-TEFb, and reverses HIV-1 latency.
Stoszko M, Al-Hatmi AMS, Skriba A, Roling M, Ne E, Crespo R, Mueller YM, Najafzadeh MJ, Kang J, Ptackova R, LeMasters E, Biswas P, Bertoldi A, Kan TW, de Crignis E, Sulc M, Lebbink JHG, Rokx C, Verbon A, van Ijcken W, Katsikis PD, Palstra RJ, Havlicek V, de Hoog S, Mahmoudi T. Stoszko M, et al. Among authors: kan tw. Sci Adv. 2020 Aug 12;6(33):eaba6617. doi: 10.1126/sciadv.aba6617. eCollection 2020 Aug. Sci Adv. 2020. PMID: 32851167 Free PMC article.
Application of human liver organoids as a patient-derived primary model for HBV infection and related hepatocellular carcinoma.
De Crignis E, Hossain T, Romal S, Carofiglio F, Moulos P, Khalid MM, Rao S, Bazrafshan A, Verstegen MM, Pourfarzad F, Koutsothanassis C, Gehart H, Kan TW, Palstra RJ, Boucher C, IJzermans JN, Huch M, Boj SF, Vries R, Clevers H, van der Laan LJ, Hatzis P, Mahmoudi T. De Crignis E, et al. Among authors: kan tw. Elife. 2021 Jul 30;10:e60747. doi: 10.7554/eLife.60747. Elife. 2021. PMID: 34328417 Free PMC article.
17 results