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Inefficient quality control of ribosome stalling during APP synthesis generates CAT-tailed species that precipitate hallmarks of Alzheimer's disease.
Rimal S, Li Y, Vartak R, Geng J, Tantray I, Li S, Huh S, Vogel H, Glabe C, Grinberg LT, Spina S, Seeley WW, Guo S, Lu B. Rimal S, et al. Among authors: li s, li y. Acta Neuropathol Commun. 2021 Oct 18;9(1):169. doi: 10.1186/s40478-021-01268-6. Acta Neuropathol Commun. 2021. PMID: 34663454 Free PMC article.
Protein products of nonstop mRNA disrupt nucleolar homeostasis.
Davis ZH, Mediani L, Antoniani F, Vinet J, Li S, Alberti S, Lu B, Holehouse AS, Carra S, Brandman O. Davis ZH, et al. Among authors: li s. Cell Stress Chaperones. 2021 May;26(3):549-561. doi: 10.1007/s12192-021-01200-w. Epub 2021 Feb 22. Cell Stress Chaperones. 2021. PMID: 33619693 Free PMC article.
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