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A Broad-Spectrum Multi-Antigen mRNA/LNP-Based Pan-Coronavirus Vaccine Induced Potent Cross-Protective Immunity Against Infection and Disease Caused by Highly Pathogenic and Heavily Spike-Mutated SARS-CoV-2 Variants of Concern in the Syrian Hamster Model.
Prakash S, Dhanushkodi NR, Singer M, Quadiri A, Zayou L, Vahed H, Coulon PG, Ibraim IC, Tafoya C, Hitchcock L, Landucci G, Forthal DN, El Babsiri A, Tifrea DF, Figueroa CJ, Nesburn AB, Kuppermann BD, Gil D, Jones TM, Ulmer JB, BenMohamed L. Prakash S, et al. bioRxiv [Preprint]. 2024 Feb 15:2024.02.14.580225. doi: 10.1101/2024.02.14.580225. bioRxiv. 2024. PMID: 38405942 Free PMC article. Preprint.
Unique Type I Interferon, Expansion/Survival Cytokines, and JAK/STAT Gene Signatures of Multifunctional Herpes Simplex Virus-Specific Effector Memory CD8+ TEM Cells Are Associated with Asymptomatic Herpes in Humans.
Vahed H, Agrawal A, Srivastava R, Prakash S, Coulon PA, Roy S, BenMohamed L. Vahed H, et al. Among authors: prakash s. J Virol. 2019 Feb 5;93(4):e01882-18. doi: 10.1128/JVI.01882-18. Print 2019 Feb 15. J Virol. 2019. PMID: 30487281 Free PMC article.
Therapeutic Mucosal Vaccination of Herpes Simplex Virus 2-Infected Guinea Pigs with Ribonucleotide Reductase 2 (RR2) Protein Boosts Antiviral Neutralizing Antibodies and Local Tissue-Resident CD4+ and CD8+ TRM Cells Associated with Protection against Recurrent Genital Herpes.
Srivastava R, Roy S, Coulon PG, Vahed H, Prakash S, Dhanushkodi N, Kim GJ, Fouladi MA, Campo J, Teng AA, Liang X, Schaefer H, BenMohamed L. Srivastava R, et al. Among authors: prakash s. J Virol. 2019 Apr 17;93(9):e02309-18. doi: 10.1128/JVI.02309-18. Print 2019 May 1. J Virol. 2019. PMID: 30787156 Free PMC article.
Blockade of PD-1 and LAG-3 Immune Checkpoints Combined with Vaccination Restores the Function of Antiviral Tissue-Resident CD8+ TRM Cells and Reduces Ocular Herpes Simplex Infection and Disease in HLA Transgenic Rabbits.
Roy S, Coulon PG, Prakash S, Srivastava R, Geertsema R, Dhanushkodi N, Lam C, Nguyen V, Gorospe E, Nguyen AM, Salazar S, Alomari NI, Warsi WR, BenMohamed L. Roy S, et al. Among authors: prakash s. J Virol. 2019 Aug 28;93(18):e00827-19. doi: 10.1128/JVI.00827-19. Print 2019 Sep 15. J Virol. 2019. PMID: 31217250 Free PMC article.
NLRP3, NLRP12, and IFI16 Inflammasomes Induction and Caspase-1 Activation Triggered by Virulent HSV-1 Strains Are Associated With Severe Corneal Inflammatory Herpetic Disease.
Coulon PG, Dhanushkodi N, Prakash S, Srivastava R, Roy S, Alomari NI, Nguyen AM, Warsi WR, Ye C, Carlos-Cruz EA, Mai UT, Cruel AC, Ekmekciyan KM, Pearlman E, BenMohamed L. Coulon PG, et al. Among authors: prakash s. Front Immunol. 2019 Jul 16;10:1631. doi: 10.3389/fimmu.2019.01631. eCollection 2019. Front Immunol. 2019. PMID: 31367214 Free PMC article.
Human Epitopes Identified from Herpes Simplex Virus Tegument Protein VP11/12 (UL46) Recall Multifunctional Effector Memory CD4+ TEM Cells in Asymptomatic Individuals and Protect from Ocular Herpes Infection and Disease in "Humanized" HLA-DR Transgenic Mice.
Srivastava R, Coulon PA, Prakash S, Dhanushkodi NR, Roy S, Nguyen AM, Alomari NI, Mai UT, Amezquita C, Ye C, Maillère B, BenMohamed L. Srivastava R, et al. Among authors: prakash s. J Virol. 2020 Mar 17;94(7):e01991-19. doi: 10.1128/JVI.01991-19. Print 2020 Mar 17. J Virol. 2020. PMID: 31915285 Free PMC article.
High Frequency of Gamma Interferon-Producing PLZFloRORγtlo Invariant Natural Killer 1 Cells Infiltrating Herpes Simplex Virus 1-Infected Corneas Is Associated with Asymptomatic Ocular Herpesvirus Infection.
Dhanushkodi NR, Srivastava R, Prakash S, Roy S, Coulon PA, Vahed H, Nguyen AM, Salazar S, Nguyen L, Amezquita C, Ye C, Nguyen V, BenMohamed L. Dhanushkodi NR, et al. Among authors: prakash s. J Virol. 2020 Apr 16;94(9):e00140-20. doi: 10.1128/JVI.00140-20. Print 2020 Apr 16. J Virol. 2020. PMID: 32102882 Free PMC article.
Upregulation of Multiple CD8+ T Cell Exhaustion Pathways Is Associated with Recurrent Ocular Herpes Simplex Virus Type 1 Infection.
Coulon PG, Roy S, Prakash S, Srivastava R, Dhanushkodi N, Salazar S, Amezquita C, Nguyen L, Vahed H, Nguyen AM, Warsi WR, Ye C, Carlos-Cruz EA, Mai UT, BenMohamed L. Coulon PG, et al. Among authors: prakash s. J Immunol. 2020 Jul 15;205(2):454-468. doi: 10.4049/jimmunol.2000131. Epub 2020 Jun 15. J Immunol. 2020. PMID: 32540992 Free PMC article.
Genome-Wide Asymptomatic B-Cell, CD4 + and CD8 + T-Cell Epitopes, that are Highly Conserved Between Human and Animal Coronaviruses, Identified from SARS-CoV-2 as Immune Targets for Pre-Emptive Pan-Coronavirus Vaccines.
Prakash S, Srivastava R, Coulon PG, Dhanushkodi NR, Chentoufi AA, Tifrea DF, Edwards RA, Figueroa CJ, Schubl SD, Hsieh L, Buchmeier MJ, Bouziane M, Nesburn AB, Kuppermann BD, BenMohamed L. Prakash S, et al. bioRxiv [Preprint]. 2020 Sep 28:2020.09.27.316018. doi: 10.1101/2020.09.27.316018. bioRxiv. 2020. Update in: J Immunol. 2021 Jun 1;206(11):2566-2582. doi: 10.4049/jimmunol.2001438 PMID: 33024971 Free PMC article. Updated. Preprint.
2,591 results