Day M - Search Results

1

TopBP1 utilises a bipartite GINS binding mode to support genome replication.

Day M, Tetik B, Parlak M, Almeida-Hernández Y, Räschle M, Kaschani F, Siegert H, Marko A, Sanchez-Garcia E, Kaiser M, Barker IA, Pearl LH, Oliver AW, Boos D. Day M, et al. Nat Commun. 2024 Feb 27;15(1):1797. doi: 10.1038/s41467-024-45946-0. Nat Commun. 2024. PMID: 38413589 Free PMC article.

2

Phosphorylation-dependent assembly of DNA damage response systems and the central roles of TOPBP1.

Day M, Oliver AW, Pearl LH. Day M, et al. DNA Repair (Amst). 2021 Dec;108:103232. doi: 10.1016/j.dnarep.2021.103232. Epub 2021 Sep 29. DNA Repair (Amst). 2021. PMID: 34678589 Free PMC article. Review.

3

Structure of the human RAD17-RFC clamp loader and 9-1-1 checkpoint clamp bound to a dsDNA-ssDNA junction.

Day M, Oliver AW, Pearl LH. Day M, et al. Nucleic Acids Res. 2022 Aug 12;50(14):8279-8289. doi: 10.1093/nar/gkac588. Nucleic Acids Res. 2022. PMID: 35819203 Free PMC article.

4

Phosphorylation-dependent assembly and coordination of the DNA damage checkpoint apparatus by Rad4(TopBP1).

Qu M, Rappas M, Wardlaw CP, Garcia V, Ren JY, Day M, Carr AM, Oliver AW, Du LL, Pearl LH. Qu M, et al. Among authors: day m. Mol Cell. 2013 Sep 26;51(6):723-736. doi: 10.1016/j.molcel.2013.08.030. Mol Cell. 2013. PMID: 24074952 Free PMC article.

5

BRCT domains of the DNA damage checkpoint proteins TOPBP1/Rad4 display distinct specificities for phosphopeptide ligands.

Day M, Rappas M, Ptasinska K, Boos D, Oliver AW, Pearl LH. Day M, et al. Elife. 2018 Oct 8;7:e39979. doi: 10.7554/eLife.39979. Elife. 2018. PMID: 30295604 Free PMC article.

6

Phosphorylation-mediated interactions with TOPBP1 couple 53BP1 and 9-1-1 to control the G1 DNA damage checkpoint.

Bigot N, Day M, Baldock RA, Watts FZ, Oliver AW, Pearl LH. Bigot N, et al. Among authors: day m. Elife. 2019 May 28;8:e44353. doi: 10.7554/eLife.44353. Elife. 2019. PMID: 31135337 Free PMC article.

7

Structural basis for recruitment of the CHK1 DNA damage kinase by the CLASPIN scaffold protein.

Day M, Parry-Morris S, Houghton-Gisby J, Oliver AW, Pearl LH. Day M, et al. Structure. 2021 Jun 3;29(6):531-539.e3. doi: 10.1016/j.str.2021.03.007. Epub 2021 Mar 30. Structure. 2021. PMID: 33789090 Free PMC article.

8

MDC1 Interacts with TOPBP1 to Maintain Chromosomal Stability during Mitosis.

Leimbacher PA, Jones SE, Shorrocks AK, de Marco Zompit M, Day M, Blaauwendraad J, Bundschuh D, Bonham S, Fischer R, Fink D, Kessler BM, Oliver AW, Pearl LH, Blackford AN, Stucki M. Leimbacher PA, et al. Among authors: day m. Mol Cell. 2019 May 2;74(3):571-583.e8. doi: 10.1016/j.molcel.2019.02.014. Epub 2019 Mar 18. Mol Cell. 2019. PMID: 30898438 Free PMC article.

9

ATM Localization and Heterochromatin Repair Depend on Direct Interaction of the 53BP1-BRCT2 Domain with γH2AX.

Baldock RA, Day M, Wilkinson OJ, Cloney R, Jeggo PA, Oliver AW, Watts FZ, Pearl LH. Baldock RA, et al. Among authors: day m. Cell Rep. 2015 Dec 15;13(10):2081-9. doi: 10.1016/j.celrep.2015.10.074. Epub 2015 Nov 25. Cell Rep. 2015. PMID: 26628370 Free PMC article.

10

CK2 Phosphorylation of Human Papillomavirus 16 E2 on Serine 23 Promotes Interaction with TopBP1 and Is Critical for E2 Interaction with Mitotic Chromatin and the Viral Life Cycle.

Prabhakar AT, James CD, Das D, Otoa R, Day M, Burgner J, Fontan CT, Wang X, Glass SH, Wieland A, Donaldson MM, Bristol ML, Li R, Oliver AW, Pearl LH, Smith BO, Morgan IM. Prabhakar AT, et al. Among authors: day m. mBio. 2021 Oct 26;12(5):e0116321. doi: 10.1128/mBio.01163-21. Epub 2021 Sep 21. mBio. 2021. PMID: 34544280 Free PMC article.

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