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Asia-Inclusive Global Development of Enpatoran: Results of an Ethno-Bridging Study, Intrinsic/Extrinsic Factor Assessments and Disease Trajectory Modeling to Inform Design of a Phase II Multiregional Clinical Trial.
Klopp-Schulze L, Gopalakrishnan S, Yalkinoglu Ö, Kuroki Y, Lu H, Goteti K, Krebs-Brown A, Nogueira Filho M, Gradhand U, Fluck M, Shaw J, Dong J, Venkatakrishnan K. Klopp-Schulze L, et al. Among authors: fluck m. Clin Pharmacol Ther. 2024 Jun;115(6):1346-1357. doi: 10.1002/cpt.3216. Epub 2024 Feb 28. Clin Pharmacol Ther. 2024. PMID: 38415785
Avelumab internalization by human circulating immune cells is mediated by both Fc gamma receptor and PD-L1 binding.
Jin H, D'Urso V, Neuteboom B, McKenna SD, Schweickhardt R, Gross AW, Fomekong Nanfack Y, Paoletti A, Carter C, Toleikis L, Fluck M, Scheuenpflug J, Cai T. Jin H, et al. Among authors: fluck m. Oncoimmunology. 2021 Aug 29;10(1):1958590. doi: 10.1080/2162402X.2021.1958590. eCollection 2021. Oncoimmunology. 2021. PMID: 34484871 Free PMC article.
In vitro characterization of sarizotan metabolism: hepatic clearance, identification and characterization of metabolites, drug-metabolizing enzyme identification, and evaluation of cytochrome p450 inhibition.
Gallemann D, Wimmer E, Höfer CC, Freisleben A, Fluck M, Ladstetter B, Dolgos H. Gallemann D, et al. Among authors: fluck m. Drug Metab Dispos. 2010 Jun;38(6):905-16. doi: 10.1124/dmd.109.029835. Epub 2010 Mar 10. Drug Metab Dispos. 2010. PMID: 20219851
231 results