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Intracellular proteomics and extracellular vesiculomics as a metric of disease recapitulation in 3D-bioprinted aortic valve arrays.
Clift CL, Blaser MC, Gerrits W, Turner ME, Sonawane A, Pham T, Andresen JL, Fenton OS, Grolman JM, Campedelli A, Buffolo F, Schoen FJ, Hjortnaes J, Muehlschlegel JD, Mooney DJ, Aikawa M, Singh SA, Langer R, Aikawa E. Clift CL, et al. Among authors: pham t. Sci Adv. 2024 Mar;10(9):eadj9793. doi: 10.1126/sciadv.adj9793. Epub 2024 Feb 28. Sci Adv. 2024. PMID: 38416823 Free PMC article.
Multiomics of Tissue Extracellular Vesicles Identifies Unique Modulators of Atherosclerosis and Calcific Aortic Valve Stenosis.
Blaser MC, Buffolo F, Halu A, Turner ME, Schlotter F, Higashi H, Pantano L, Clift CL, Saddic LA, Atkins SK, Rogers MA, Pham T, Vromman A, Shvartz E, Sukhova GK, Monticone S, Camussi G, Robson SC, Body SC, Muehlschlegel JD, Singh SA, Aikawa M, Aikawa E. Blaser MC, et al. Among authors: pham t. Circulation. 2023 Aug 22;148(8):661-678. doi: 10.1161/CIRCULATIONAHA.122.063402. Epub 2023 Jul 10. Circulation. 2023. PMID: 37427430 Free PMC article.
Spatiotemporal Multi-Omics Mapping Generates a Molecular Atlas of the Aortic Valve and Reveals Networks Driving Disease.
Schlotter F, Halu A, Goto S, Blaser MC, Body SC, Lee LH, Higashi H, DeLaughter DM, Hutcheson JD, Vyas P, Pham T, Rogers MA, Sharma A, Seidman CE, Loscalzo J, Seidman JG, Aikawa M, Singh SA, Aikawa E. Schlotter F, et al. Among authors: pham t. Circulation. 2018 Jul 24;138(4):377-393. doi: 10.1161/CIRCULATIONAHA.117.032291. Circulation. 2018. PMID: 29588317 Free PMC article.
ApoC-III is a novel inducer of calcification in human aortic valves.
Schlotter F, de Freitas RCC, Rogers MA, Blaser MC, Wu PJ, Higashi H, Halu A, Iqbal F, Andraski AB, Rodia CN, Kuraoka S, Wen JR, Creager M, Pham T, Hutcheson JD, Body SC, Kohan AB, Sacks FM, Aikawa M, Singh SA, Aikawa E. Schlotter F, et al. Among authors: pham t. J Biol Chem. 2021 Jan-Jun;296:100193. doi: 10.1074/jbc.RA120.015700. Epub 2021 Jan 6. J Biol Chem. 2021. PMID: 33334888 Free PMC article.
Elastogenesis Correlates With Pigment Production in Murine Aortic Valve Leaflets.
Hutcheson JD, Schlotter F, Creager MD, Li X, Pham T, Vyas P, Higashi H, Body SC, Aikawa M, Singh SA, Kos L, Aikawa E. Hutcheson JD, et al. Among authors: pham t. Front Cardiovasc Med. 2021 Jun 22;8:678401. doi: 10.3389/fcvm.2021.678401. eCollection 2021. Front Cardiovasc Med. 2021. PMID: 34239903 Free PMC article.
NLRP3 Inflammasome Activation in Peripheral Arterial Disease.
Bartoli-Leonard F, Zimmer J, Sonawane AR, Perez K, Turner ME, Kuraoka S, Pham T, Li F, Aikawa M, Singh S, Brewster L, Aikawa E. Bartoli-Leonard F, et al. Among authors: pham t. J Am Heart Assoc. 2023 Mar 21;12(6):e026945. doi: 10.1161/JAHA.122.026945. Epub 2023 Mar 9. J Am Heart Assoc. 2023. PMID: 36892058 Free PMC article.
Directional Endothelial Communication by Polarized Extracellular Vesicle Release.
Raju S, Botts SR, Blaser MC, Abdul-Samad M, Prajapati K, Khosraviani N, Ho TWW, Breda LCD, Ching C, Galant NJ, Fiddes L, Wu R, Clift CL, Pham T, Lee WL, Singh SA, Aikawa E, Fish JE, Howe KL. Raju S, et al. Among authors: pham t. Circ Res. 2024 Feb 2;134(3):269-289. doi: 10.1161/CIRCRESAHA.123.322993. Epub 2024 Jan 4. Circ Res. 2024. PMID: 38174557 Free PMC article.
5,205 results