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Page 1
Endothelial cells drive organ fibrosis in mice by inducing expression of the transcription factor SOX9.
Trogisch FA, Abouissa A, Keles M, Birke A, Fuhrmann M, Dittrich GM, Weinzierl N, Wink E, Cordero J, Elsherbiny A, Martin-Garrido A, Grein S, Hemanna S, Hofmann E, Nicin L, Bibli SI, Airik R, Kispert A, Kist R, Quanchao S, Kürschner SW, Winkler M, Gretz N, Mogler C, Korff T, Koch PS, Dimmeler S, Dobreva G, Heineke J. Trogisch FA, et al. Among authors: heineke j. Sci Transl Med. 2024 Feb 28;16(736):eabq4581. doi: 10.1126/scitranslmed.abq4581. Epub 2024 Feb 28. Sci Transl Med. 2024. PMID: 38416842
Blood-based microRNA signatures differentiate various forms of cardiac hypertrophy.
Derda AA, Thum S, Lorenzen JM, Bavendiek U, Heineke J, Keyser B, Stuhrmann M, Givens RC, Kennel PJ, Schulze PC, Widder JD, Bauersachs J, Thum T. Derda AA, et al. Among authors: heineke j. Int J Cardiol. 2015 Oct 1;196:115-22. doi: 10.1016/j.ijcard.2015.05.185. Epub 2015 Jun 5. Int J Cardiol. 2015. PMID: 26086795 Free PMC article.
GATA6 promotes angiogenic function and survival in endothelial cells by suppression of autocrine transforming growth factor beta/activin receptor-like kinase 5 signaling.
Froese N, Kattih B, Breitbart A, Grund A, Geffers R, Molkentin JD, Kispert A, Wollert KC, Drexler H, Heineke J. Froese N, et al. Among authors: heineke j. J Biol Chem. 2011 Feb 18;286(7):5680-90. doi: 10.1074/jbc.M110.176925. Epub 2010 Dec 2. J Biol Chem. 2011. PMID: 21127043 Free PMC article.
The transcription factor GATA4 promotes myocardial regeneration in neonatal mice.
Malek Mohammadi M, Kattih B, Grund A, Froese N, Korf-Klingebiel M, Gigina A, Schrameck U, Rudat C, Liang Q, Kispert A, Wollert KC, Bauersachs J, Heineke J. Malek Mohammadi M, et al. Among authors: heineke j. EMBO Mol Med. 2017 Feb;9(2):265-279. doi: 10.15252/emmm.201606602. EMBO Mol Med. 2017. PMID: 28053183 Free PMC article.
Hepatic Endothelial Notch Activation Protects against Liver Metastasis by Regulating Endothelial-Tumor Cell Adhesion Independent of Angiocrine Signaling.
Wohlfeil SA, Häfele V, Dietsch B, Schledzewski K, Winkler M, Zierow J, Leibing T, Mohammadi MM, Heineke J, Sticht C, Olsavszky V, Koch PS, Géraud C, Goerdt S. Wohlfeil SA, et al. Among authors: heineke j. Cancer Res. 2019 Feb 1;79(3):598-610. doi: 10.1158/0008-5472.CAN-18-1752. Epub 2018 Dec 10. Cancer Res. 2019. PMID: 30530502
Inactivation of Sox9 in fibroblasts reduces cardiac fibrosis and inflammation.
Scharf GM, Kilian K, Cordero J, Wang Y, Grund A, Hofmann M, Froese N, Wang X, Kispert A, Kist R, Conway SJ, Geffers R, Wollert KC, Dobreva G, Bauersachs J, Heineke J. Scharf GM, et al. Among authors: heineke j. JCI Insight. 2019 Jul 16;5(15):e126721. doi: 10.1172/jci.insight.126721. JCI Insight. 2019. PMID: 31310588 Free PMC article.
Induction of cardiomyocyte proliferation and angiogenesis protects neonatal mice from pressure overload-associated maladaptation.
Malek Mohammadi M, Abouissa A, Azizah I, Xie Y, Cordero J, Shirvani A, Gigina A, Engelhardt M, Trogisch FA, Geffers R, Dobreva G, Bauersachs J, Heineke J. Malek Mohammadi M, et al. Among authors: heineke j. JCI Insight. 2019 Jul 23;5(16):e128336. doi: 10.1172/jci.insight.128336. JCI Insight. 2019. PMID: 31335322 Free PMC article.
87 results