Liu S - Search Results

1

Backbone Modification Provides a Long-Acting Inverse Agonist of Pathogenic, Constitutively Active PTH1R Variants.

Liu S, Daley EJ, Tran LM, Yu Z, Reyes M, Dean T, Khatri A, Levine PM, Balana AT, Pratt MR, Jüppner H, Gellman SH, Gardella TJ. Liu S, et al. J Am Chem Soc. 2024 Mar 13;146(10):6522-6529. doi: 10.1021/jacs.3c09694. Epub 2024 Feb 28. J Am Chem Soc. 2024. PMID: 38417010

2

Use of Backbone Modification To Enlarge the Spatiotemporal Diversity of Parathyroid Hormone Receptor-1 Signaling via Biased Agonism.

Liu S, Jean-Alphonse FG, White AD, Wootten D, Sexton PM, Gardella TJ, Vilardaga JP, Gellman SH. Liu S, et al. J Am Chem Soc. 2019 Sep 18;141(37):14486-14490. doi: 10.1021/jacs.9b04179. Epub 2019 Sep 9. J Am Chem Soc. 2019. PMID: 31496241 Free PMC article.

3

Receptor selectivity from minimal backbone modification of a polypeptide agonist.

Liu S, Cheloha RW, Watanabe T, Gardella TJ, Gellman SH. Liu S, et al. Proc Natl Acad Sci U S A. 2018 Dec 4;115(49):12383-12388. doi: 10.1073/pnas.1815294115. Epub 2018 Nov 15. Proc Natl Acad Sci U S A. 2018. PMID: 30442659 Free PMC article.

4

Altered signaling at the PTH receptor via modified agonist contacts with the extracellular domain provides a path to prolonged agonism in vivo.

Liu S, Yu Z, Daley EJ, Bingman CA, Bruchs AT, Gardella TJ, Gellman SH. Liu S, et al. Proc Natl Acad Sci U S A. 2022 Nov 29;119(48):e2212736119. doi: 10.1073/pnas.2212736119. Epub 2022 Nov 21. Proc Natl Acad Sci U S A. 2022. PMID: 36409914 Free PMC article.

5

Preparation of β²-Homologous Amino Acids Bearing Polar Side Chains via a Collective Synthesis Strategy.

Liu S, Gellman SH. Liu S, et al. J Org Chem. 2020 Feb 7;85(3):1718-1724. doi: 10.1021/acs.joc.9b02562. Epub 2020 Jan 10. J Org Chem. 2020. PMID: 31920080 Free PMC article.

6

Spatial bias in cAMP generation determines biological responses to PTH type 1 receptor activation.

White AD, Peña KA, Clark LJ, Maria CS, Liu S, Jean-Alphonse FG, Lee JY, Lei S, Cheng Z, Tu CL, Fang F, Szeto N, Gardella TJ, Xiao K, Gellman SH, Bahar I, Sutkeviciute I, Chang W, Vilardaga JP. White AD, et al. Among authors: liu s. Sci Signal. 2021 Oct 5;14(703):eabc5944. doi: 10.1126/scisignal.abc5944. Epub 2021 Oct 5. Sci Signal. 2021. PMID: 34609896 Free PMC article.

7

Recognition of Class II MHC Peptide Ligands That Contain β-Amino Acids.

Cheloha RW, Woodham AW, Bousbaine D, Wang T, Liu S, Sidney J, Sette A, Gellman SH, Ploegh HL. Cheloha RW, et al. Among authors: liu s. J Immunol. 2019 Sep 15;203(6):1619-1628. doi: 10.4049/jimmunol.1900536. Epub 2019 Aug 7. J Immunol. 2019. PMID: 31391235 Free PMC article.

8

G_q/11-dependent regulation of endosomal cAMP generation by parathyroid hormone class B GPCR.

White AD, Jean-Alphonse FG, Fang F, Peña KA, Liu S, König GM, Inoue A, Aslanoglou D, Gellman SH, Kostenis E, Xiao K, Vilardaga JP. White AD, et al. Among authors: liu s. Proc Natl Acad Sci U S A. 2020 Mar 31;117(13):7455-7460. doi: 10.1073/pnas.1918158117. Epub 2020 Mar 17. Proc Natl Acad Sci U S A. 2020. PMID: 32184323 Free PMC article.

9

Examining the Impact of Diet-and-Exercise-Induced Weight Loss on Drug Metabolism and Gastric Emptying in Patients with Obesity.

Liu S, Wang L, Miller N, Waltje A, Abdelnabi M, Zhu HJ, Sun D, Rothberg AE, Pai MP. Liu S, et al. J Clin Pharmacol. 2025 Jan 22. doi: 10.1002/jcph.6192. Online ahead of print. J Clin Pharmacol. 2025. PMID: 39840538

10

Swords and shields: the war between Candidatus Liberibacter asiaticus and citrus.

Hu Y, Lu N, Bao K, Liu S, Li R, Huang G. Hu Y, et al. Among authors: liu s. Front Plant Sci. 2025 Jan 7;15:1518880. doi: 10.3389/fpls.2024.1518880. eCollection 2024. Front Plant Sci. 2025. PMID: 39840363 Free PMC article. Review.

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