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Page 1
Rare SH2B3 coding variants in lupus patients impair B cell tolerance and predispose to autoimmunity.
Zhang Y, Morris R, Brown GJ, Lorenzo AMD, Meng X, Kershaw NJ, Kiridena P, Burgio G, Gross S, Cappello JY, Shen Q, Wang H, Turnbull C, Lea-Henry T, Stanley M, Yu Z, Ballard FD, Chuah A, Lee JC, Hatch AM, Enders A, Masters SL, Headley AP, Trnka P, Mallon D, Fletcher JT, Walters GD, Šestan M, Jelušić M, Cook MC, Athanasopoulos V, Fulcher DA, Babon JJ, Vinuesa CG, Ellyard JI. Zhang Y, et al. Among authors: ballard fd. J Exp Med. 2024 Apr 1;221(4):e20221080. doi: 10.1084/jem.20221080. Epub 2024 Feb 28. J Exp Med. 2024. PMID: 38417019 Free PMC article.
Zeb2 drives the formation of CD11c+ atypical B cells to sustain germinal centers that control persistent infection.
Gao X, Shen Q, Roco JA, Dalton B, Frith K, Munier CML, Ballard FD, Wang K, Kelly HG, Nekrasov M, He JS, Jaeger R, Carreira P, Ellyard JI, Beattie L, Enders A, Cook MC, Zaunders JJ, Cockburn IA. Gao X, et al. Among authors: ballard fd. Sci Immunol. 2024 Mar 29;9(93):eadj4748. doi: 10.1126/sciimmunol.adj4748. Epub 2024 Mar 29. Sci Immunol. 2024. PMID: 38330097
DOCK2 Deficiency Causes Defects in Antiviral T-Cell Responses and Impaired Control of Herpes Simplex Virus Infection.
Randall KL, Flesch IEA, Mei Y, Miosge LA, Aye R, Yu Z, Domaschenz H, Hollett NA, Russell TA, Stefanovic T, Wong YC, Seneviratne S, Ballard F, Hernandez Gallardo R, Croft SN, Goodnow CC, Bertram EM, Enders A, Tscharke DC. Randall KL, et al. J Infect Dis. 2024 Sep 23;230(3):e712-e721. doi: 10.1093/infdis/jiae077. J Infect Dis. 2024. PMID: 38366567 Free PMC article.
L-plastin associated syndrome of immune deficiency and hematologic cytopenia.
Hernandez RA, Hearn JI, Bhoopalan V, Hamzeh AR, Kwong K, Diamand K, Davies A, Li FJ, Padmanabhan H, Milne R, Ballard F, Spensberger D, Gardiner EE, Miraghazadeh B, Enders A, Cook MC. Hernandez RA, et al. J Allergy Clin Immunol. 2024 Sep;154(3):767-777. doi: 10.1016/j.jaci.2024.05.001. Epub 2024 May 6. J Allergy Clin Immunol. 2024. PMID: 38710235 Free article.