McElvaney NG - Search Results

1

Monocyte NLRP3 inflammasome and interleukin-1β activation modulated by alpha-1 antitrypsin therapy in deficient individuals.

Gogoi D, Yu H, Casey M, Baird R, Yusuf A, Forde L, O' Brien ME, West JR, Flagg T, McElvaney NG, Eden E, Mueller C, Brantly ML, Geraghty P, Reeves EP. Gogoi D, et al. Among authors: mcelvaney ng. Thorax. 2024 Aug 19;79(9):822-833. doi: 10.1136/thorax-2023-221071. Thorax. 2024. PMID: 38418195 Free PMC article.

2

Baseline characteristics of enrollees in the National Heart, Lung and Blood Institute Registry of alpha 1-antitrypsin deficiency. Alpha 1-Antitrypsin Deficiency Registry Study Group.

McElvaney NG, Stoller JK, Buist AS, Prakash UB, Brantly ML, Schluchter MD, Crystal RD. McElvaney NG, et al. Chest. 1997 Feb;111(2):394-403. doi: 10.1378/chest.111.2.394. Chest. 1997. PMID: 9041988

3

Z alpha1-antitrypsin polymerizes in the lung and acts as a neutrophil chemoattractant.

Mulgrew AT, Taggart CC, Lawless MW, Greene CM, Brantly ML, O'Neill SJ, McElvaney NG. Mulgrew AT, et al. Among authors: mcelvaney ng. Chest. 2004 May;125(5):1952-7. doi: 10.1378/chest.125.5.1952. Chest. 2004. PMID: 15136414

4

Antimicrobial proteins and polypeptides in pulmonary innate defence.

Rogan MP, Geraghty P, Greene CM, O'Neill SJ, Taggart CC, McElvaney NG. Rogan MP, et al. Among authors: mcelvaney ng. Respir Res. 2006 Feb 17;7(1):29. doi: 10.1186/1465-9921-7-29. Respir Res. 2006. PMID: 16503962 Free PMC article. Review.

5

Neutrophil elastase up-regulates cathepsin B and matrix metalloprotease-2 expression.

Geraghty P, Rogan MP, Greene CM, Boxio RM, Poiriert T, O'Mahony M, Belaaouaj A, O'Neill SJ, Taggart CC, McElvaney NG. Geraghty P, et al. Among authors: mcelvaney ng. J Immunol. 2007 May 1;178(9):5871-8. doi: 10.4049/jimmunol.178.9.5871. J Immunol. 2007. PMID: 17442971 Free article.

6

Secretory leucocyte protease inhibitor inhibits interferon-gamma-induced cathepsin S expression.

Geraghty P, Greene CM, O'Mahony M, O'Neill SJ, Taggart CC, McElvaney NG. Geraghty P, et al. Among authors: mcelvaney ng. J Biol Chem. 2007 Nov 16;282(46):33389-33395. doi: 10.1074/jbc.M706884200. Epub 2007 Sep 18. J Biol Chem. 2007. PMID: 17878156 Free article.

7

Alpha-1-antitrypsin aerosolised augmentation abrogates neutrophil elastase-induced expression of cathepsin B and matrix metalloprotease 2 in vivo and in vitro.

Geraghty P, Rogan MP, Greene CM, Brantly ML, O'Neill SJ, Taggart CC, McElvaney NG. Geraghty P, et al. Among authors: mcelvaney ng. Thorax. 2008 Jul;63(7):621-6. doi: 10.1136/thx.2007.088559. Epub 2008 Feb 4. Thorax. 2008. PMID: 18250185

8

Activation of the epidermal growth factor receptor (EGFR) by a novel metalloprotease pathway.

Bergin DA, Greene CM, Sterchi EE, Kenna C, Geraghty P, Belaaouaj A, Taggart CC, O'Neill SJ, McElvaney NG. Bergin DA, et al. Among authors: mcelvaney ng. J Biol Chem. 2008 Nov 14;283(46):31736-44. doi: 10.1074/jbc.M803732200. Epub 2008 Sep 4. J Biol Chem. 2008. PMID: 18772136 Free article.

9

Heritability of lung function in severe alpha-1 antitrypsin deficiency.

DeMeo DL, Campbell EJ, Brantly ML, Barker AF, Eden E, McElvaney NG, Rennard SI, Stocks JM, Stoller JK, Strange C, Turino G, Sandhaus RA, Silverman EK. DeMeo DL, et al. Among authors: mcelvaney ng. Hum Hered. 2009;67(1):38-45. doi: 10.1159/000164397. Epub 2008 Oct 17. Hum Hered. 2009. PMID: 18931508

10

LL-37 complexation with glycosaminoglycans in cystic fibrosis lungs inhibits antimicrobial activity, which can be restored by hypertonic saline.

Bergsson G, Reeves EP, McNally P, Chotirmall SH, Greene CM, Greally P, Murphy P, O'Neill SJ, McElvaney NG. Bergsson G, et al. Among authors: mcelvaney ng. J Immunol. 2009 Jul 1;183(1):543-51. doi: 10.4049/jimmunol.0803959. J Immunol. 2009. PMID: 19542465

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