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33 results

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Kinetic Profiling of RAS Mutations With Circulating Tumor DNA in the Canadian Cancer Trials Group CO.26 Trial Suggests the Loss of RAS Mutations in Neo-RAS-Wildtype Metastatic Colorectal Cancer Is Transient.
Wu FTH, Topham JT, O'Callaghan CJ, Feilotter H, Kennecke HF, Drusbosky L, Renouf DJ, Jonker DJ, Tu D, Chen EX, Loree JM. Wu FTH, et al. Among authors: topham jt. JCO Precis Oncol. 2024 Aug;8:e2400031. doi: 10.1200/PO.24.00031. JCO Precis Oncol. 2024. PMID: 39178370 Free PMC article. Clinical Trial.
Homologous recombination deficiency signatures in gastrointestinal and thoracic cancers correlate with platinum therapy duration.
Tsang ES, Csizmok V, Williamson LM, Pleasance E, Topham JT, Karasinska JM, Titmuss E, Schrader I, Yip S, Tessier-Cloutier B, Mungall K, Ng T, Sun S, Lim HJ, Loree JM, Laskin J, Marra MA, Jones SJM, Schaeffer DF, Renouf DJ. Tsang ES, et al. Among authors: topham jt. NPJ Precis Oncol. 2023 Mar 24;7(1):31. doi: 10.1038/s41698-023-00368-x. NPJ Precis Oncol. 2023. PMID: 36964191 Free PMC article.
Optimizing the number of variants tracked to follow disease burden with circulating tumor DNA assays in metastatic colorectal cancer.
Boutin M, Topham JT, Feilotter H, Kennecke HF, Couture F, Harb M, Kavan P, Berry S, Lim HJ, Goffin JR, Ahmad C, Lott A, Renouf DJ, Jonker DJ, Tu D, O'Callaghan CJ, Chen EX, Loree JM. Boutin M, et al. Among authors: topham jt. Ther Adv Med Oncol. 2023 Jun 22;15:17588359231183682. doi: 10.1177/17588359231183682. eCollection 2023. Ther Adv Med Oncol. 2023. PMID: 37389190 Free PMC article.
MicroRNA Expression-Based Model Indicates Event-Free Survival in Pediatric Acute Myeloid Leukemia.
Lim EL, Trinh DL, Ries RE, Wang J, Gerbing RB, Ma Y, Topham J, Hughes M, Pleasance E, Mungall AJ, Moore R, Zhao Y, Aplenc R, Sung L, Kolb EA, Gamis A, Smith M, Gerhard DS, Alonzo TA, Meshinchi S, Marra MA. Lim EL, et al. J Clin Oncol. 2017 Dec 10;35(35):3964-3977. doi: 10.1200/JCO.2017.74.7451. Epub 2017 Oct 25. J Clin Oncol. 2017. PMID: 29068783 Free PMC article.
The Neoantigen Landscape of the Coding and Noncoding Cancer Genome Space.
Lau TTY, Sefid Dashti ZJ, Titmuss E, Pender A, Topham JT, Bridgers J, Loree JM, Feng X, Pleasance ED, Renouf DJ, Schrader KA, Sun S, Ho C, Marra MA, Laskin J, Karsan A. Lau TTY, et al. Among authors: topham jt. J Mol Diagn. 2022 Jun;24(6):609-618. doi: 10.1016/j.jmoldx.2022.02.004. Epub 2022 Mar 31. J Mol Diagn. 2022. PMID: 35367630 Free article.
Pancreatic cancer tumor organoids exhibit subtype-specific differences in metabolic profiles.
Ali HA, Karasinska JM, Topham JT, Johal D, Kalloger S, Metcalfe A, Warren CS, Miyagi A, Tao LV, Kevorkova M, Chafe SC, McDonald PC, Dedhar S, Parker SJ, Renouf DJ, Schaeffer DF. Ali HA, et al. Among authors: topham jt. Cancer Metab. 2024 Oct 3;12(1):28. doi: 10.1186/s40170-024-00357-z. Cancer Metab. 2024. PMID: 39363341 Free PMC article.
33 results