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29 results

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Page 1
BCL-XL inhibitors enhance the apoptotic efficacy of BRAF inhibitors in BRAFV600E colorectal cancer.
Jenkins LJ, Luk IY, Chionh F, Tan T, Needham K, Ayton J, Reehorst CM, Vukelic N, Sieber OM, Mouradov D, Gibbs P, Williams DS, Tebbutt NC, Desai J, Hollande F, Dhillon AS, Lee EF, Merino D, Fairlie WD, Mariadason JM. Jenkins LJ, et al. Among authors: chionh f. Cell Death Dis. 2024 Mar 1;15(3):183. doi: 10.1038/s41419-024-06478-z. Cell Death Dis. 2024. PMID: 38429301 Free PMC article.
DUSP5 is methylated in CIMP-high colorectal cancer but is not a major regulator of intestinal cell proliferation and tumorigenesis.
Tögel L, Nightingale R, Wu R, Chüeh AC, Al-Obaidi S, Luk I, Dávalos-Salas M, Chionh F, Murone C, Buchanan DD, Chatterton Z, Sieber OM, Arango D, Tebbutt NC, Williams D, Dhillon AS, Mariadason JM. Tögel L, et al. Among authors: chionh f. Sci Rep. 2018 Jan 29;8(1):1767. doi: 10.1038/s41598-018-20176-9. Sci Rep. 2018. PMID: 29379130 Free PMC article.
Genotype-Tailored ERK/MAPK Pathway and HDAC Inhibition Rewires the Apoptotic Rheostat to Trigger Colorectal Cancer Cell Death.
Jenkins LJ, Luk IY, Fairlie WD, Lee EF, Palmieri M, Schoffer KL, Tan T, Ng I, Vukelic N, Tran S, Tse JWT, Nightingale R, Alam Z, Chionh F, Iatropoulos G, Ernst M, Afshar-Sterle S, Desai J, Gibbs P, Sieber OM, Dhillon AS, Tebbutt NC, Mariadason JM. Jenkins LJ, et al. Among authors: chionh f. Mol Cancer Ther. 2023 Jan 3;22(1):52-62. doi: 10.1158/1535-7163.MCT-22-0101. Mol Cancer Ther. 2023. PMID: 36343387 Free PMC article.
Genomic Profiling of Biliary Tract Cancer Cell Lines Reveals Molecular Subtypes and Actionable Drug Targets.
Lau DK, Mouradov D, Wasenang W, Luk IY, Scott CM, Williams DS, Yeung YH, Limpaiboon T, Iatropoulos GF, Jenkins LJ, Reehorst CM, Chionh F, Nikfarjam M, Croagh D, Dhillon AS, Weickhardt AJ, Muramatsu T, Saito Y, Tebbutt NC, Sieber OM, Mariadason JM. Lau DK, et al. Among authors: chionh f. iScience. 2019 Nov 22;21:624-637. doi: 10.1016/j.isci.2019.10.044. Epub 2019 Oct 31. iScience. 2019. PMID: 31731200 Free PMC article.
Rapid Resistance of FGFR-driven Gastric Cancers to Regorafenib and Targeted FGFR Inhibitors can be Overcome by Parallel Inhibition of MEK.
Lau DK, Luk IY, Jenkins LJ, Martin A, Williams DS, Schoffer KL, Chionh F, Buchert M, Sjoquist K, Boussioutas A, Hayes SA, Ernst M, Weickhardt AJ, Pavlakis N, Tebbutt NC, Mariadason JM. Lau DK, et al. Among authors: chionh f. Mol Cancer Ther. 2021 Apr;20(4):704-715. doi: 10.1158/1535-7163.MCT-20-0836. Epub 2021 Feb 9. Mol Cancer Ther. 2021. PMID: 33563752 Clinical Trial.
Author Correction: DUSP5 is methylated in CIMP-high colorectal cancer but is not a major regulator of intestinal cell proliferation and tumorigenesis.
Tögel L, Nightingale R, Wu R, Chüeh AC, Al-Obaidi S, Luk I, Dávalos-Salas M, Chionh F, Murone C, Buchanan DD, Chatterton Z, Sieber OM, Arango D, Tebbutt NC, Williams D, Dhillon AS, Mariadason JM. Tögel L, et al. Among authors: chionh f. Sci Rep. 2023 Feb 10;13(1):2422. doi: 10.1038/s41598-023-29328-y. Sci Rep. 2023. PMID: 36765160 Free PMC article. No abstract available.
VEGF-A, VEGFR1 and VEGFR2 single nucleotide polymorphisms and outcomes from the AGITG MAX trial of capecitabine, bevacizumab and mitomycin C in metastatic colorectal cancer.
Chionh F, Gebski V, Al-Obaidi SJ, Mooi JK, Bruhn MA, Lee CK, Chüeh AC, Williams DS, Weickhardt AJ, Wilson K, Scott AM, Simes J, Hardingham JE, Price TJ, Mariadason JM, Tebbutt NC. Chionh F, et al. Sci Rep. 2022 Jan 24;12(1):1238. doi: 10.1038/s41598-021-03952-y. Sci Rep. 2022. PMID: 35075138 Free PMC article. Clinical Trial.
Dual Antiangiogenesis Agents Bevacizumab Plus Trebananib, without Chemotherapy, in First-line Treatment of Metastatic Colorectal Cancer: Results of a Phase II Study.
Mooi J, Chionh F, Savas P, Da Gama Duarte J, Chong G, Brown S, Wong R, Price TJ, Wann A, Skrinos E, Mariadason JM, Tebbutt NC. Mooi J, et al. Among authors: chionh f. Clin Cancer Res. 2021 Apr 15;27(8):2159-2167. doi: 10.1158/1078-0432.CCR-20-2714. Epub 2021 Jan 29. Clin Cancer Res. 2021. PMID: 33514526 Clinical Trial.
29 results