El-Zoghbi MS - Search Results

1

Design, synthesis and mechanistic study of new dual targeting HDAC/tubulin inhibitors.

El-Zoghbi MS, Bass AK, A Abuo-Rahma GE, Mohamed MF, Badr M, Al-Ghulikah HA, Abdelhafez EM. El-Zoghbi MS, et al. Future Med Chem. 2024 Apr;16(7):601-622. doi: 10.4155/fmc-2023-0336. Epub 2024 Mar 4. Future Med Chem. 2024. PMID: 38436113 Free article.

2

Comprehensive review for anticancer hybridized multitargeting HDAC inhibitors.

Bass AKA, El-Zoghbi MS, Nageeb EM, Mohamed MFA, Badr M, Abuo-Rahma GEA. Bass AKA, et al. Eur J Med Chem. 2021 Jan 1;209:112904. doi: 10.1016/j.ejmech.2020.112904. Epub 2020 Oct 8. Eur J Med Chem. 2021. PMID: 33077264 Review.

3

Utilization of cyanopyridine in design and synthesis of first-in-class anticancer dual acting PIM-1 kinase/HDAC inhibitors.

Bass AKA, Nageeb EM, El-Zoghbi MS, Mohamed MFA, Badr M, Abuo-Rahma GEA. Bass AKA, et al. Among authors: el zoghbi ms. Bioorg Chem. 2022 Feb;119:105564. doi: 10.1016/j.bioorg.2021.105564. Epub 2021 Dec 16. Bioorg Chem. 2022. PMID: 34959179

4

Design, synthesis, docking, and anticancer evaluations of new thiazolo[3,2-a] pyrimidines as topoisomerase II inhibitors.

El-Zoghbi MS, El-Sebaey SA, Al-Ghulikah HA, Sobh EA. El-Zoghbi MS, et al. J Enzyme Inhib Med Chem. 2023 Dec;38(1):2175209. doi: 10.1080/14756366.2023.2175209. J Enzyme Inhib Med Chem. 2023. PMID: 36776024 Free PMC article.

5

New Pyrimidine-5-Carbonitriles as COX-2 Inhibitors: Design, Synthesis, Anticancer Screening, Molecular Docking, and In Silico ADME Profile Studies.

Al-Ghulikah HA, El-Sebaey SA, Bass AKA, El-Zoghbi MS. Al-Ghulikah HA, et al. Among authors: el zoghbi ms. Molecules. 2022 Nov 2;27(21):7485. doi: 10.3390/molecules27217485. Molecules. 2022. PMID: 36364312 Free PMC article.

6

Novel Aminopyrimidine-2,4-diones, 2-Thiopyrimidine-4-ones, and 6-Arylpteridines as Dual-Target Inhibitors of BRD4/PLK1: Design, Synthesis, Cytotoxicity, and Computational Studies.

El-Kalyoubi S, El-Sebaey SA, Elfeky SM, Al-Ghulikah HA, El-Zoghbi MS. El-Kalyoubi S, et al. Among authors: el zoghbi ms. Pharmaceuticals (Basel). 2023 Sep 15;16(9):1303. doi: 10.3390/ph16091303. Pharmaceuticals (Basel). 2023. PMID: 37765111 Free PMC article.

7

Aminopyridone-linked benzimidazoles: a fragment-based drug design for the development of CDK9 inhibitors.

Husseiny EM, Abulkhair HS, El-Hddad SS, Osama N, El-Zoghbi MS. Husseiny EM, et al. Among authors: el zoghbi ms. Future Med Chem. 2023 Jul;15(14):1213-1232. doi: 10.4155/fmc-2023-0139. Epub 2023 Aug 16. Future Med Chem. 2023. PMID: 37584185

8

Synthesis of certain benzothieno[3,2-d]pyrimidine derivatives as a selective SIRT2 inhibitors.

Khalil NA, Ahmed EM, Zaher AF, El-Zoghbi MS, Sobh EA. Khalil NA, et al. Eur J Med Chem. 2020 Feb 1;187:111926. doi: 10.1016/j.ejmech.2019.111926. Epub 2019 Nov 30. Eur J Med Chem. 2020. PMID: 31812033

9

New benzothieno[2,3-c]pyridines as non-steroidal CYP17 inhibitors: design, synthesis, anticancer screening, apoptosis induction, and in silico ADME profile studies.

Khalil NA, Ahmed EM, Zaher AF, Sobh EA, El-Sebaey SA, El-Zoghbi MS. Khalil NA, et al. Among authors: el zoghbi ms. J Enzyme Inhib Med Chem. 2021 Dec;36(1):1839-1859. doi: 10.1080/14756366.2021.1958212. J Enzyme Inhib Med Chem. 2021. PMID: 34338119 Free PMC article.

10

New benzothienopyran and benzothienopyranopyrimidine derivatives as topoisomerase I inhibitors: Design, synthesis, anticancer screening, apoptosis induction and molecular modeling studies.

Khalil NA, Ahmed EM, Zaher AF, Alhamaky SM, Osama N, El-Zoghbi MS. Khalil NA, et al. Among authors: el zoghbi ms. Bioorg Chem. 2023 Aug;137:106638. doi: 10.1016/j.bioorg.2023.106638. Epub 2023 May 27. Bioorg Chem. 2023. PMID: 37257374

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