Mohamed MF - Search Results

1

Design, synthesis and mechanistic study of new dual targeting HDAC/tubulin inhibitors.

El-Zoghbi MS, Bass AK, A Abuo-Rahma GE, Mohamed MF, Badr M, Al-Ghulikah HA, Abdelhafez EM. El-Zoghbi MS, et al. Among authors: mohamed mf. Future Med Chem. 2024 Apr;16(7):601-622. doi: 10.4155/fmc-2023-0336. Epub 2024 Mar 4. Future Med Chem. 2024. PMID: 38436113

2

Design, synthesis, docking studies and biological evaluation of novel chalcone derivatives as potential histone deacetylase inhibitors.

Mohamed MFA, Shaykoon MSA, Abdelrahman MH, Elsadek BEM, Aboraia AS, Abuo-Rahma GEAA. Mohamed MFA, et al. Bioorg Chem. 2017 Jun;72:32-41. doi: 10.1016/j.bioorg.2017.03.005. Epub 2017 Mar 19. Bioorg Chem. 2017. PMID: 28346873

3

Design, synthesis, mechanistic and histopathological studies of small-molecules of novel indole-2-carboxamides and pyrazino[1,2-a]indol-1(2H)-ones as potential anticancer agents effecting the reactive oxygen species production.

Youssif BGM, Abdelrahman MH, Abdelazeem AH, Abdelgawad MA, Ibrahim HM, Salem OIA, Mohamed MFA, Treambleau L, Bukhari SNA. Youssif BGM, et al. Eur J Med Chem. 2018 Feb 25;146:260-273. doi: 10.1016/j.ejmech.2018.01.042. Epub 2018 Jan 31. Eur J Med Chem. 2018. PMID: 29407956

4

Design, synthesis and anticancer activity of novel valproic acid conjugates with improved histone deacetylase (HDAC) inhibitory activity.

Ibrahim TS, Sheha TA, Abo-Dya NE, AlAwadh MA, Alhakamy NA, Abdel-Samii ZK, Panda SS, Abuo-Rahma GEA, Mohamed MFA. Ibrahim TS, et al. Bioorg Chem. 2020 Jun;99:103797. doi: 10.1016/j.bioorg.2020.103797. Epub 2020 Mar 30. Bioorg Chem. 2020. PMID: 32247939

5

Comprehensive review for anticancer hybridized multitargeting HDAC inhibitors.

Bass AKA, El-Zoghbi MS, Nageeb EM, Mohamed MFA, Badr M, Abuo-Rahma GEA. Bass AKA, et al. Eur J Med Chem. 2021 Jan 1;209:112904. doi: 10.1016/j.ejmech.2020.112904. Epub 2020 Oct 8. Eur J Med Chem. 2021. PMID: 33077264 Review.

6

Synthesis, antitumor, antibacterial and urease inhibitory evaluation of new piperazinyl N-4 carbamoyl functionalized ciprofloxacin derivatives.

Abdel-Aal MAA, Shaykoon MSA, Abuo-Rahma GEAA, Mohamed MFA, Badr M, Abdel-Aziz SA. Abdel-Aal MAA, et al. Pharmacol Rep. 2021 Jun;73(3):891-906. doi: 10.1007/s43440-020-00193-0. Epub 2021 Jan 3. Pharmacol Rep. 2021. PMID: 33389728

7

Design, Synthesis, In Vitro Anticancer Evaluation and Molecular Modelling Studies of 3,4,5-Trimethoxyphenyl-Based Derivatives as Dual EGFR/HDAC Hybrid Inhibitors.

Ibrahim TS, Malebari AM, Mohamed MFA. Ibrahim TS, et al. Pharmaceuticals (Basel). 2021 Nov 17;14(11):1177. doi: 10.3390/ph14111177. Pharmaceuticals (Basel). 2021. PMID: 34832959 Free PMC article.

8

Utilization of cyanopyridine in design and synthesis of first-in-class anticancer dual acting PIM-1 kinase/HDAC inhibitors.

Bass AKA, Nageeb EM, El-Zoghbi MS, Mohamed MFA, Badr M, Abuo-Rahma GEA. Bass AKA, et al. Bioorg Chem. 2022 Feb;119:105564. doi: 10.1016/j.bioorg.2021.105564. Epub 2021 Dec 16. Bioorg Chem. 2022. PMID: 34959179

9

Novel pyrrol-2(3H)-ones and pyridazin-3(2H)-ones carrying quinoline scaffold as anti-proliferative tubulin polymerization inhibitors.

Abdelbaset MS, Abuo-Rahma GEA, Abdelrahman MH, Ramadan M, Youssif BGM, Bukhari SNA, Mohamed MFA, Abdel-Aziz M. Abdelbaset MS, et al. Bioorg Chem. 2018 Oct;80:151-163. doi: 10.1016/j.bioorg.2018.06.003. Epub 2018 Jun 5. Bioorg Chem. 2018. PMID: 29920422

10

Novel aryl carboximidamide and 3-aryl-1,2,4-oxadiazole analogues of naproxen as dual selective COX-2/15-LOX inhibitors: Design, synthesis and docking studies.

Youssif BGM, Mohamed MFA, Al-Sanea MM, Moustafa AH, Abdelhamid AA, Gomaa HAM. Youssif BGM, et al. Bioorg Chem. 2019 Apr;85:577-584. doi: 10.1016/j.bioorg.2019.02.043. Epub 2019 Feb 20. Bioorg Chem. 2019. PMID: 30878890

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