Urich E - Search Results

1

B cell depletion with anti-CD20 promotes neuroprotection in a BAFF-dependent manner in mice and humans.

Wang AA, Luessi F, Neziraj T, Pössnecker E, Zuo M, Engel S, Hanuscheck N, Florescu A, Bugbee E, Ma XI, Rana F, Lee D, Ward LA, Kuhle J, Himbert J, Schraad M, van Puijenbroek E, Klein C, Urich E, Ramaglia V, Pröbstel AK, Zipp F, Gommerman JL. Wang AA, et al. Among authors: urich e. Sci Transl Med. 2024 Mar 6;16(737):eadi0295. doi: 10.1126/scitranslmed.adi0295. Epub 2024 Mar 6. Sci Transl Med. 2024. PMID: 38446903

2

Effects of a Fully Humanized Type II Anti-CD20 Monoclonal Antibody on Peripheral and CNS B Cells in a Transgenic Mouse Model of Multiple Sclerosis.

Tacke S, Chunder R, Schropp V, Urich E, Kuerten S. Tacke S, et al. Among authors: urich e. Int J Mol Sci. 2022 Mar 15;23(6):3172. doi: 10.3390/ijms23063172. Int J Mol Sci. 2022. PMID: 35328594 Free PMC article.

3

Obinutuzumab-Induced B Cell Depletion Reduces Spinal Cord Pathology in a CD20 Double Transgenic Mouse Model of Multiple Sclerosis.

Breakell T, Tacke S, Schropp V, Zetterberg H, Blennow K, Urich E, Kuerten S. Breakell T, et al. Among authors: urich e. Int J Mol Sci. 2020 Sep 18;21(18):6864. doi: 10.3390/ijms21186864. Int J Mol Sci. 2020. PMID: 32962135 Free PMC article.

4

Anti-CD20 Disrupts Meningeal B-Cell Aggregates in a Model of Secondary Progressive Multiple Sclerosis.

Roodselaar J, Zhou Y, Leppert D, Hauser AE, Urich E, Anthony DC. Roodselaar J, et al. Among authors: urich e. Neurol Neuroimmunol Neuroinflamm. 2021 Mar 2;8(3):e975. doi: 10.1212/NXI.0000000000000975. Print 2021 May. Neurol Neuroimmunol Neuroinflamm. 2021. PMID: 33653962 Free PMC article.

5

Interleukin 18-independent engagement of interleukin 18 receptor-alpha is required for autoimmune inflammation.

Gutcher I, Urich E, Wolter K, Prinz M, Becher B. Gutcher I, et al. Among authors: urich e. Nat Immunol. 2006 Sep;7(9):946-53. doi: 10.1038/ni1377. Epub 2006 Aug 13. Nat Immunol. 2006. PMID: 16906165 Free article.

6

Autoantibody-mediated demyelination depends on complement activation but not activatory Fc-receptors.

Urich E, Gutcher I, Prinz M, Becher B. Urich E, et al. Proc Natl Acad Sci U S A. 2006 Dec 5;103(49):18697-702. doi: 10.1073/pnas.0607283103. Epub 2006 Nov 22. Proc Natl Acad Sci U S A. 2006. PMID: 17121989 Free PMC article.

7

Transcriptional profiling of human brain endothelial cells reveals key properties crucial for predictive in vitro blood-brain barrier models.

Urich E, Lazic SE, Molnos J, Wells I, Freskgård PO. Urich E, et al. PLoS One. 2012;7(5):e38149. doi: 10.1371/journal.pone.0038149. Epub 2012 May 31. PLoS One. 2012. PMID: 22675443 Free PMC article.

8

Brain Shuttle Neprilysin reduces central Amyloid-β levels.

Campos CR, Kemble AM, Niewoehner J, Freskgård PO, Urich E. Campos CR, et al. Among authors: urich e. PLoS One. 2020 Mar 10;15(3):e0229850. doi: 10.1371/journal.pone.0229850. eCollection 2020. PLoS One. 2020. PMID: 32155191 Free PMC article.

9

Antibody therapies in CNS diseases.

Freskgård PO, Urich E. Freskgård PO, et al. Among authors: urich e. Neuropharmacology. 2017 Jul 1;120:38-55. doi: 10.1016/j.neuropharm.2016.03.014. Epub 2016 Mar 10. Neuropharmacology. 2017. PMID: 26972827 Review.

10

Cell-type-specific cis-eQTLs in eight human brain cell types identify novel risk genes for psychiatric and neurological disorders.

Bryois J, Calini D, Macnair W, Foo L, Urich E, Ortmann W, Iglesias VA, Selvaraj S, Nutma E, Marzin M, Amor S, Williams A, Castelo-Branco G, Menon V, De Jager P, Malhotra D. Bryois J, et al. Among authors: urich e. Nat Neurosci. 2022 Aug;25(8):1104-1112. doi: 10.1038/s41593-022-01128-z. Epub 2022 Aug 1. Nat Neurosci. 2022. PMID: 35915177

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