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TET2 coactivates gene expression through demethylation of enhancers.
Wang L, Ozark PA, Smith ER, Zhao Z, Marshall SA, Rendleman EJ, Piunti A, Ryan C, Whelan AL, Helmin KA, Morgan MA, Zou L, Singer BD, Shilatifard A. Wang L, et al. Among authors: singer bd. Sci Adv. 2018 Nov 7;4(11):eaau6986. doi: 10.1126/sciadv.aau6986. eCollection 2018 Nov. Sci Adv. 2018. PMID: 30417100 Free PMC article.
Uncoupling histone H3K4 trimethylation from developmental gene expression via an equilibrium of COMPASS, Polycomb and DNA methylation.
Douillet D, Sze CC, Ryan C, Piunti A, Shah AP, Ugarenko M, Marshall SA, Rendleman EJ, Zha D, Helmin KA, Zhao Z, Cao K, Morgan MA, Singer BD, Bartom ET, Smith ER, Shilatifard A. Douillet D, et al. Among authors: singer bd. Nat Genet. 2020 Jun;52(6):615-625. doi: 10.1038/s41588-020-0618-1. Epub 2020 May 11. Nat Genet. 2020. PMID: 32393859 Free PMC article.
PAX9 Determines Epigenetic State Transition and Cell Fate in Cancer.
Zhao Z, Szczepanski AP, Tsuboyama N, Abdala-Valencia H, Goo YA, Singer BD, Bartom ET, Yue F, Wang L. Zhao Z, et al. Among authors: singer bd. Cancer Res. 2021 Sep 15;81(18):4696-4708. doi: 10.1158/0008-5472.CAN-21-1114. Epub 2021 Aug 2. Cancer Res. 2021. PMID: 34341073 Free PMC article.
Mediator complex subunit 1 architects a tumorigenic Treg cell program independent of inflammation.
Chaudhuri SM, Weinberg SE, Wang D, Yalom LK, Montauti E, Iyer R, Tang AY, Torres Acosta MA, Shen J, Mani NL, Wang S, Liu K, Lu W, Bui TM, Manzanares LD, Dehghani Z, Wai CM, Gao B, Wei J, Yue F, Cui W, Singer BD, Sumagin R, Zhang Y, Fang D. Chaudhuri SM, et al. Among authors: singer bd. Cell Rep Med. 2024 Mar 19;5(3):101441. doi: 10.1016/j.xcrm.2024.101441. Epub 2024 Feb 29. Cell Rep Med. 2024. PMID: 38428427 Free PMC article.
Circuits between infected macrophages and T cells in SARS-CoV-2 pneumonia.
Grant RA, Morales-Nebreda L, Markov NS, Swaminathan S, Querrey M, Guzman ER, Abbott DA, Donnelly HK, Donayre A, Goldberg IA, Klug ZM, Borkowski N, Lu Z, Kihshen H, Politanska Y, Sichizya L, Kang M, Shilatifard A, Qi C, Lomasney JW, Argento AC, Kruser JM, Malsin ES, Pickens CO, Smith SB, Walter JM, Pawlowski AE, Schneider D, Nannapaneni P, Abdala-Valencia H, Bharat A, Gottardi CJ, Budinger GRS, Misharin AV, Singer BD, Wunderink RG; NU SCRIPT Study Investigators. Grant RA, et al. Among authors: singer bd. Nature. 2021 Feb;590(7847):635-641. doi: 10.1038/s41586-020-03148-w. Epub 2021 Jan 11. Nature. 2021. PMID: 33429418 Free PMC article.
Distinctive evolution of alveolar T cell responses is associated with clinical outcomes in unvaccinated patients with SARS-CoV-2 pneumonia.
Markov NS, Ren Z, Senkow KJ, Grant RA, Gao CA, Malsin ES, Sichizya L, Kihshen H, Helmin KA, Jovisic M, Arnold JM, Pérez-Leonor XG, Abdala-Valencia H, Swaminathan S, Nwaezeapu J, Kang M, Rasmussen L, Ozer EA, Lorenzo-Redondo R, Hultquist JF, Simons LM, Rios-Guzman E, Misharin AV, Wunderink RG, Budinger GRS, Singer BD, Morales-Nebreda L; NU SCRIPT Study Investigators. Markov NS, et al. Among authors: singer bd. Nat Immunol. 2024 Sep;25(9):1607-1622. doi: 10.1038/s41590-024-01914-w. Epub 2024 Aug 13. Nat Immunol. 2024. PMID: 39138384
Aging is associated with a systemic length-associated transcriptome imbalance.
Stoeger T, Grant RA, McQuattie-Pimentel AC, Anekalla KR, Liu SS, Tejedor-Navarro H, Singer BD, Abdala-Valencia H, Schwake M, Tetreault MP, Perlman H, Balch WE, Chandel NS, Ridge KM, Sznajder JI, Morimoto RI, Misharin AV, Budinger GRS, Nunes Amaral LA. Stoeger T, et al. Among authors: singer bd. Nat Aging. 2022 Dec;2(12):1191-1206. doi: 10.1038/s43587-022-00317-6. Epub 2022 Dec 9. Nat Aging. 2022. PMID: 37118543 Free PMC article.
Age-Dependent Differences in T-Cell Responses to Influenza A Virus.
Prigge AD, Ma R, Coates BM, Singer BD, Ridge KM. Prigge AD, et al. Among authors: singer bd. Am J Respir Cell Mol Biol. 2020 Oct;63(4):415-423. doi: 10.1165/rcmb.2020-0169TR. Am J Respir Cell Mol Biol. 2020. PMID: 32609537 Free PMC article. Review.
115 results