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Thrombopoietin mimetic stimulates bone marrow vascular and stromal niches to mitigate acute radiation syndrome.
Vercellino J, Małachowska B, Kulkarni S, Bell BI, Shajahan S, Shinoda K, Eichenbaum G, Verma AK, Ghosh SP, Yang WL, Frenette PS, Guha C. Vercellino J, et al. Among authors: guha c. Res Sq [Preprint]. 2024 Feb 19:rs.3.rs-3946910. doi: 10.21203/rs.3.rs-3946910/v1. Res Sq. 2024. Update in: Stem Cell Res Ther. 2024 Apr 29;15(1):123. doi: 10.1186/s13287-024-03734-z PMID: 38463959 Free PMC article. Updated. Preprint.
Snai2 Maintains Bone Marrow Niche Cells by Repressing Osteopontin Expression.
Wei Q, Nakahara F, Asada N, Zhang D, Gao X, Xu C, Alfieri A, Brodin NP, Zimmerman SE, Mar JC, Guha C, Guo W, Frenette PS. Wei Q, et al. Among authors: guha c. Dev Cell. 2020 Jun 8;53(5):503-513.e5. doi: 10.1016/j.devcel.2020.04.012. Epub 2020 May 14. Dev Cell. 2020. PMID: 32413329 Free PMC article.
The thrombopoietin mimetic JNJ-26366821 increases megakaryopoiesis without affecting malignant myeloid proliferation.
Adrianzen-Herrera D, Choudhary G, Gordon-Mitchell S, Ramachandra N, Bhagat T, Zhang H, Aluri S, Shastri A, Steidl U, Will B, Yang WL, Mahler M, Eichenbaum G, Guha C, Verma A. Adrianzen-Herrera D, et al. Among authors: guha c. Leuk Lymphoma. 2020 Oct;61(10):2453-2465. doi: 10.1080/10428194.2020.1775213. Epub 2020 Jun 24. Leuk Lymphoma. 2020. PMID: 32578476 Free article.
Extracellular Vesicles for the Treatment of Radiation Injuries.
Nanduri LSY, Duddempudi PK, Yang WL, Tamarat R, Guha C. Nanduri LSY, et al. Among authors: guha c. Front Pharmacol. 2021 May 18;12:662437. doi: 10.3389/fphar.2021.662437. eCollection 2021. Front Pharmacol. 2021. PMID: 34084138 Free PMC article. Review.
Repurposing Radiation Therapy for Immuno-oncology.
Tang J, Malachowska B, Wu X, Guha C. Tang J, et al. Among authors: guha c. Clin Oncol (R Coll Radiol). 2021 Nov;33(11):683-693. doi: 10.1016/j.clon.2021.08.015. Epub 2021 Sep 14. Clin Oncol (R Coll Radiol). 2021. PMID: 34535358 Free article. Review.
Orthovoltage X-Rays Exhibit Increased Efficacy Compared with γ-Rays in Preclinical Irradiation.
Bell BI, Vercellino J, Brodin NP, Velten C, Nanduri LSY, Nagesh PKB, Tanaka KE, Fang Y, Wang Y, Macedo R, English J, Schumacher MM, Duddempudi PK, Asp P, Koba W, Shajahan S, Liu L, Tomé WA, Yang WL, Kolesnick R, Guha C. Bell BI, et al. Among authors: guha c. Cancer Res. 2022 Aug 3;82(15):2678-2691. doi: 10.1158/0008-5472.CAN-22-0656. Cancer Res. 2022. PMID: 35919990 Free PMC article.
313 results