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Genetic regulation and targeted reversal of lysosomal dysfunction and inflammatory sterol metabolism in pulmonary arterial hypertension.
Harvey LD, Alotaibi M, Kim HJ, Tai YY, Tang Y, Sun W, El Khoury W, Woodcock CC, Aaraj YA, St Croix CM, Stolz DB, Lee J, Cheng MH, Schwantes-An TH, Desai AA, Pauciulo MW, Nichols WC, Webb A, Lafyatis R, Nouraie M, Wu H, McDonald JG, Chauvet C, Cheng S, Bahar I, Bertero T, Benza RL, Jain M, Chan SY. Harvey LD, et al. Among authors: mcdonald jg. bioRxiv [Preprint]. 2024 Mar 1:2024.02.26.582142. doi: 10.1101/2024.02.26.582142. bioRxiv. 2024. PMID: 38464060 Free PMC article. Preprint.
Female sex hormones exacerbate retinal neurodegeneration.
Rowe AA, Reyes S, Velasquez MJ, Yee T, Nettesheim ER, McDonald JG, Wert KJ. Rowe AA, et al. Among authors: mcdonald jg. bioRxiv [Preprint]. 2024 Jul 16:2024.07.11.603104. doi: 10.1101/2024.07.11.603104. bioRxiv. 2024. PMID: 39071341 Free PMC article. Preprint.
Statin-mediated reduction in mitochondrial cholesterol primes an anti-inflammatory response in macrophages by upregulating JMJD3.
Saiioum Z, Dauner K, Li YF, Verma N, Almendro-Vedia V, Valdivieso Gonzalez D, Zhang DJ, Nakka K, McDonald J, Sorisky A, Song BL, Lopez Montero I, Luo J, Dilworth J, Zha X. Saiioum Z, et al. bioRxiv [Preprint]. 2024 Mar 3:2023.01.09.523264. doi: 10.1101/2023.01.09.523264. bioRxiv. 2024. Update in: Elife. 2024 Apr 11;13:e85964. doi: 10.7554/eLife.85964 PMID: 36711703 Free PMC article. Updated. Preprint.
Plasma Concentrations of Multiple Oxysterols and Risk of Colorectal Adenomas.
Passarelli MN, McDonald JG, Thompson BM, Pomares-Millan H, Palys TJ, Rees JR, Barry EL. Passarelli MN, et al. Among authors: mcdonald jg. Cancer Prev Res (Phila). 2024 Nov 4;17(11):517-524. doi: 10.1158/1940-6207.CAPR-24-0108. Cancer Prev Res (Phila). 2024. PMID: 39223695 Clinical Trial.
138 results