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A Direct Comparison of rAAV5 Variants Derived from the Baculovirus Expression System Using LC-MS Workflows Demonstrates Key Differences in Overall Production Yield, Product Quality and Vector Efficiency.
Guapo F, Donohue N, Strasser L, Boi S, Füssl F, Rainbow-Fletcher A, Getty P, Anderson I, Barron N, Bones J. Guapo F, et al. Among authors: bones j. Int J Mol Sci. 2024 Feb 28;25(5):2785. doi: 10.3390/ijms25052785. Int J Mol Sci. 2024. PMID: 38474031 Free PMC article.
Improvements in single-use bioreactor film material composition leads to robust and reliable Chinese hamster ovary cell performance.
Kelly PS, Dorival-García N, Paré S, Carillo S, Ta C, Alarcon Miguez A, Coleman O, Harper E, Shannon M, Henry M, Connolly L, Clynes M, Meleady P, Bones J, Barron N. Kelly PS, et al. Among authors: bones j. Biotechnol Prog. 2019 Jul;35(4):e2824. doi: 10.1002/btpr.2824. Epub 2019 May 6. Biotechnol Prog. 2019. PMID: 31017345
Inter-laboratory study of an optimised peptide mapping workflow using automated trypsin digestion for monitoring monoclonal antibody product quality attributes.
Millán-Martín S, Jakes C, Carillo S, Buchanan T, Guender M, Kristensen DB, Sloth TM, Ørgaard M, Cook K, Bones J. Millán-Martín S, et al. Among authors: bones j. Anal Bioanal Chem. 2020 Oct;412(25):6833-6848. doi: 10.1007/s00216-020-02809-z. Epub 2020 Jul 25. Anal Bioanal Chem. 2020. PMID: 32710279 Free PMC article.
Optimisation of the use of sliding window deconvolution for comprehensive characterisation of trastuzumab and adalimumab charge variants by native high resolution mass spectrometry.
Millán-Martín S, Carillo S, Füssl F, Sutton J, Gazis P, Cook K, Scheffler K, Bones J. Millán-Martín S, et al. Among authors: bones j. Eur J Pharm Biopharm. 2021 Jan;158:83-95. doi: 10.1016/j.ejpb.2020.11.006. Epub 2020 Nov 16. Eur J Pharm Biopharm. 2021. PMID: 33212184 Free article.
Simultaneous monitoring of multiple attributes of pyrrolobenzodiazepine antibody-drug conjugates by size exclusion chromatography - high resolution mass spectrometry.
Füssl F, Barry CS, Pugh KM, Chooi KP, Vijayakrishnan B, Kang GD, von Bulow C, Howard PW, Bones J. Füssl F, et al. Among authors: bones j. J Pharm Biomed Anal. 2021 Oct 25;205:114287. doi: 10.1016/j.jpba.2021.114287. Epub 2021 Jul 28. J Pharm Biomed Anal. 2021. PMID: 34385015 Free article.
115 results