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Corrigendum to Pro-cognitive effects of dual tacrine derivatives acting as cholinesterase inhibitors and NMDA receptor antagonists "Biomed. Pharmacother. 176 (2024) 116821".
Chvojkova M, Kolar D, Kovacova K, Cejkova L, Misiachna A, Hakenova K, Gorecki L, Horak M, Korabecny J, Soukup O, Vales K. Chvojkova M, et al. Among authors: misiachna a. Biomed Pharmacother. 2024 Dec;181:117660. doi: 10.1016/j.biopha.2024.117660. Epub 2024 Nov 4. Biomed Pharmacother. 2024. PMID: 39500698 Free article. No abstract available.
Dizocilpine derivatives as neuroprotective NMDA receptor antagonists without psychomimetic side effects.
Konecny J, Misiachna A, Chvojkova M, Kleteckova L, Kolcheva M, Novak M, Prchal L, Ladislav M, Hemelikova K, Netolicky J, Hrabinova M, Kobrlova T, Karasova JZ, Pejchal J, Fibigar J, Vecera Z, Kucera T, Jendelova P, Zahumenska P, Langore E, Doderovic J, Pang YP, Vales K, Korabecny J, Soukup O, Horak M. Konecny J, et al. Among authors: misiachna a. Eur J Med Chem. 2024 Dec 15;280:116981. doi: 10.1016/j.ejmech.2024.116981. Epub 2024 Oct 18. Eur J Med Chem. 2024. PMID: 39442339 Free article.
Potent and reversible open-channel blocker of NMDA receptor derived from dizocilpine with enhanced membrane-to-channel inhibition.
Misiachna A, Konecny J, Kolcheva M, Ladislav M, Prchal L, Netolicky J, Kortus S, Zahumenska P, Langore E, Novak M, Hemelikova K, Hermanova Z, Hrochova M, Pelikanova A, Odvarkova J, Pejchal J, Kassa J, Zdarova Karasova J, Korabecny J, Soukup O, Horak M. Misiachna A, et al. Biomed Pharmacother. 2024 Sep;178:117201. doi: 10.1016/j.biopha.2024.117201. Epub 2024 Jul 24. Biomed Pharmacother. 2024. PMID: 39053419 Free article.
Morphing cholinesterase inhibitor amiridine into multipotent drugs for the treatment of Alzheimer's disease.
Mezeiova E, Prchal L, Hrabinova M, Muckova L, Pulkrabkova L, Soukup O, Misiachna A, Janousek J, Fibigar J, Kucera T, Horak M, Makhaeva GF, Korabecny J. Mezeiova E, et al. Among authors: misiachna a. Biomed Pharmacother. 2024 Apr;173:116399. doi: 10.1016/j.biopha.2024.116399. Epub 2024 Mar 15. Biomed Pharmacother. 2024. PMID: 38492439 Free article.
Phenoxytacrine derivatives: Low-toxicity neuroprotectants exerting affinity to ifenprodil-binding site and cholinesterase inhibition.
Misiachna A, Svobodova B, Netolicky J, Chvojkova M, Kleteckova L, Prchal L, Novak M, Hrabinova M, Kucera T, Muckova L, Moravcova Z, Karasova JZ, Pejchal J, Blazek F, Malinak D, Hakenova K, Krausova BH, Kolcheva M, Ladislav M, Korabecny J, Pahnke J, Vales K, Horak M, Soukup O. Misiachna A, et al. Eur J Med Chem. 2024 Feb 15;266:116130. doi: 10.1016/j.ejmech.2024.116130. Epub 2024 Jan 7. Eur J Med Chem. 2024. PMID: 38218127 Free article.
Structure-Guided Design of N-Methylpropargylamino-Quinazoline Derivatives as Multipotent Agents for the Treatment of Alzheimer's Disease.
Svobodova B, Pulkrabkova L, Panek D, Misiachna A, Kolcheva M, Andrys R, Handl J, Capek J, Nyvltova P, Rousar T, Prchal L, Hepnarova V, Hrabinova M, Muckova L, Tosnerova D, Karabanovich G, Finger V, Soukup O, Horak M, Korabecny J. Svobodova B, et al. Among authors: misiachna a. Int J Mol Sci. 2023 May 23;24(11):9124. doi: 10.3390/ijms24119124. Int J Mol Sci. 2023. PMID: 37298087 Free PMC article.
Subunit-Dependent Surface Mobility and Localization of NMDA Receptors in Hippocampal Neurons Measured Using Nanobody Probes.
Kortus S, Rehakova K, Klima M, Kolcheva M, Ladislav M, Langore E, Barackova P, Netolicky J, Misiachna A, Hemelikova K, Humpolickova J, Chalupska D, Silhan J, Kaniakova M, Hrcka Krausova B, Boura E, Zapotocky M, Horak M. Kortus S, et al. Among authors: misiachna a. J Neurosci. 2023 Jun 28;43(26):4755-4774. doi: 10.1523/JNEUROSCI.2014-22.2023. Epub 2023 Jun 7. J Neurosci. 2023. PMID: 37286354 Free PMC article.
The pathogenic N650K variant in the GluN1 subunit regulates the trafficking, conductance, and pharmacological properties of NMDA receptors.
Kolcheva M, Ladislav M, Netolicky J, Kortus S, Rehakova K, Krausova BH, Hemelikova K, Misiachna A, Kadkova A, Klima M, Chalupska D, Horak M. Kolcheva M, et al. Among authors: misiachna a. Neuropharmacology. 2023 Jan 1;222:109297. doi: 10.1016/j.neuropharm.2022.109297. Epub 2022 Nov 1. Neuropharmacology. 2023. PMID: 36341805 Free article.
Structure-activity relationships of dually-acting acetylcholinesterase inhibitors derived from tacrine on N-methyl-d-Aspartate receptors.
Gorecki L, Misiachna A, Damborsky J, Dolezal R, Korabecny J, Cejkova L, Hakenova K, Chvojkova M, Karasova JZ, Prchal L, Novak M, Kolcheva M, Kortus S, Vales K, Horak M, Soukup O. Gorecki L, et al. Among authors: misiachna a. Eur J Med Chem. 2021 Jul 5;219:113434. doi: 10.1016/j.ejmech.2021.113434. Epub 2021 Apr 20. Eur J Med Chem. 2021. PMID: 33892271 Free article.
12 results