Lynch DR - Search Results

1

A peptide derived from TID1S rescues frataxin deficiency and mitochondrial defects in FRDA cellular models.

Dong YN, Ngaba LV, An J, Adeshina MW, Warren N, Wong J, Lynch DR. Dong YN, et al. Among authors: lynch dr. Front Pharmacol. 2024 Mar 1;15:1352311. doi: 10.3389/fphar.2024.1352311. eCollection 2024. Front Pharmacol. 2024. PMID: 38495102 Free PMC article.

2

Interactions of postsynaptic density-95 and the NMDA receptor 2 subunit control calpain-mediated cleavage of the NMDA receptor.

Dong YN, Waxman EA, Lynch DR. Dong YN, et al. Among authors: lynch dr. J Neurosci. 2004 Dec 8;24(49):11035-45. doi: 10.1523/JNEUROSCI.3722-04.2004. J Neurosci. 2004. PMID: 15590920 Free PMC article.

3

Developmental and cell-selective variations in N-methyl-D-aspartate receptor degradation by calpain.

Dong YN, Wu HY, Hsu FC, Coulter DA, Lynch DR. Dong YN, et al. Among authors: lynch dr. J Neurochem. 2006 Oct;99(1):206-17. doi: 10.1111/j.1471-4159.2006.04096.x. Epub 2006 Aug 8. J Neurochem. 2006. PMID: 16899064 Free PMC article.

4

Open-label pilot study of interferon gamma-1b in Friedreich ataxia.

Seyer L, Greeley N, Foerster D, Strawser C, Gelbard S, Dong Y, Schadt K, Cotticelli MG, Brocht A, Farmer J, Wilson RB, Lynch DR. Seyer L, et al. Among authors: lynch dr. Acta Neurol Scand. 2015 Jul;132(1):7-15. doi: 10.1111/ane.12337. Epub 2014 Oct 21. Acta Neurol Scand. 2015. PMID: 25335475 Clinical Trial.

5

Early cerebellar deficits in mitochondrial biogenesis and respiratory chain complexes in the KIKO mouse model of Friedreich ataxia.

Lin H, Magrane J, Rattelle A, Stepanova A, Galkin A, Clark EM, Dong YN, Halawani SM, Lynch DR. Lin H, et al. Among authors: lynch dr. Dis Model Mech. 2017 Nov 1;10(11):1343-1352. doi: 10.1242/dmm.030502. Dis Model Mech. 2017. PMID: 29125827 Free PMC article.

6

Early VGLUT1-specific parallel fiber synaptic deficits and dysregulated cerebellar circuit in the KIKO mouse model of Friedreich ataxia.

Lin H, Magrane J, Clark EM, Halawani SM, Warren N, Rattelle A, Lynch DR. Lin H, et al. Among authors: lynch dr. Dis Model Mech. 2017 Dec 19;10(12):1529-1538. doi: 10.1242/dmm.030049. Dis Model Mech. 2017. PMID: 29259026 Free PMC article.

7

Anti-NMDA Receptor Encephalitis: Clinical Features and Basic Mechanisms.

Lynch DR, Rattelle A, Dong YN, Roslin K, Gleichman AJ, Panzer JA. Lynch DR, et al. Adv Pharmacol. 2018;82:235-260. doi: 10.1016/bs.apha.2017.08.005. Epub 2017 Nov 8. Adv Pharmacol. 2018. PMID: 29413523 Review.

8

GRP75 overexpression rescues frataxin deficiency and mitochondrial phenotypes in Friedreich ataxia cellular models.

Dong YN, McMillan E, Clark EM, Lin H, Lynch DR. Dong YN, et al. Among authors: lynch dr. Hum Mol Genet. 2019 May 15;28(10):1594-1607. doi: 10.1093/hmg/ddy448. Hum Mol Genet. 2019. PMID: 30590615 Free PMC article.

9

Randomized, double-blind, placebo-controlled study of interferon-γ 1b in Friedreich Ataxia.

Lynch DR, Hauser L, McCormick A, Wells M, Dong YN, McCormack S, Schadt K, Perlman S, Subramony SH, Mathews KD, Brocht A, Ball J, Perdok R, Grahn A, Vescio T, Sherman JW, Farmer JM. Lynch DR, et al. Ann Clin Transl Neurol. 2019 Feb 27;6(3):546-553. doi: 10.1002/acn3.731. eCollection 2019 Mar. Ann Clin Transl Neurol. 2019. PMID: 30911578 Free PMC article. Clinical Trial.

10

Open-label pilot study of oral methylprednisolone for the treatment of patients with friedreich ataxia.

Patel M, Schadt K, McCormick A, Isaacs C, Dong YN, Lynch DR. Patel M, et al. Among authors: lynch dr. Muscle Nerve. 2019 Nov;60(5):571-575. doi: 10.1002/mus.26610. Epub 2019 Jun 30. Muscle Nerve. 2019. PMID: 31206761

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