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Crimean-Congo Hemorrhagic Fever Survivors Elicit Protective Non-Neutralizing Antibodies that Target 11 Overlapping Regions on Viral Glycoprotein GP38.
Shin OS, Monticelli SR, Hjorth CK, Hornet V, Doyle M, Abelson D, Kuehne AI, Wang A, Bakken RR, Mishra A, Middlecamp M, Champney E, Stuart L, Maurer DP, Li J, Berrigan J, Barajas J, Balinandi S, Lutwama JJ, Lobel L, Zeitlin L, Walker LM, Dye JM, Chandran K, Herbert AS, Pauli NT, McLellan JS. Shin OS, et al. Among authors: chandran k. bioRxiv [Preprint]. 2024 Mar 6:2024.03.02.583110. doi: 10.1101/2024.03.02.583110. bioRxiv. 2024. Update in: Cell Rep. 2024 Jul 23;43(7):114502. doi: 10.1016/j.celrep.2024.114502 PMID: 38496658 Free PMC article. Updated. Preprint.
Distinct pathway for evolution of enhanced receptor binding and cell entry in SARS-like bat coronaviruses.
Tse AL, Acreman CM, Ricardo-Lax I, Berrigan J, Lasso G, Balogun T, Kearns FL, Casalino L, McClain GL, Chandran AM, Lemeunier C, Amaro RE, Rice CM, Jangra RK, McLellan JS, Chandran K, Miller EH. Tse AL, et al. Among authors: chandran k, chandran am. bioRxiv [Preprint]. 2024 Jul 13:2024.06.24.600393. doi: 10.1101/2024.06.24.600393. bioRxiv. 2024. Update in: PLoS Pathog. 2024 Nov 15;20(11):e1012704. doi: 10.1371/journal.ppat.1012704 PMID: 38979151 Free PMC article. Updated. Preprint.
A viral vaccine design harnessing prior BCG immunization confers protection against Ebola virus.
Ng TW, Furuyama W, Wirchnianski AS, Saavedra-Ávila NA, Johndrow CT, Chandran K, Jacobs WR, Marzi A, Porcelli SA. Ng TW, et al. Among authors: chandran k. bioRxiv [Preprint]. 2024 May 29:2024.05.28.595735. doi: 10.1101/2024.05.28.595735. bioRxiv. 2024. Update in: Front Immunol. 2024 Jul 16;15:1429909. doi: 10.3389/fimmu.2024.1429909 PMID: 38853867 Free PMC article. Updated. Preprint.
A VHH single-domain platform enabling discovery and development of monospecific antibodies and modular neutralizing bispecifics against SARS-CoV-2 variants.
Yang ML, Yuan TZ, Chan KY, Ding L, Han Z, Franco H, Holliday C, Kannan S, Davidson E, Doranz BJ, Chandran K, Miller EH, Plante JA, Weaver SC, Cho E, Kailasan S, Marsalek L, Giang H, Abdiche Y, Sato AK. Yang ML, et al. Among authors: chandran k. Antib Ther. 2024 May 3;7(2):164-176. doi: 10.1093/abt/tbae009. eCollection 2024 Apr. Antib Ther. 2024. PMID: 38933534 Free PMC article.
Distinct pathways for evolution of enhanced receptor binding and cell entry in SARS-like bat coronaviruses.
Tse AL, Acreman CM, Ricardo-Lax I, Berrigan J, Lasso G, Balogun T, Kearns FL, Casalino L, McClain GL, Chandran AM, Lemeunier C, Amaro RE, Rice CM, Jangra RK, McLellan JS, Chandran K, Miller EH. Tse AL, et al. Among authors: chandran k. PLoS Pathog. 2024 Nov 15;20(11):e1012704. doi: 10.1371/journal.ppat.1012704. eCollection 2024 Nov. PLoS Pathog. 2024. PMID: 39546542 Free PMC article.
Limited Short-Term Evolution of SARS-CoV-2 RNA-Dependent RNA Polymerase under Remdesivir Exposure in Upper Respiratory Compartments.
Novitsky V, Beckwith CG, Carpenter-Azevedo K, Shin J, Hague J, Sam S, Steingrimsson J, Huard RC, Lethbridge K, Sahu S, Rapoza K, Chandran K, Bazerman L, Hipolito E, Diaz I, Carnevale D, Guang A, Gillani F, Caliendo AM, Kantor R. Novitsky V, et al. Among authors: chandran k. Viruses. 2024 Sep 24;16(10):1511. doi: 10.3390/v16101511. Viruses. 2024. PMID: 39459846 Free PMC article.
536 results