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Page 1
Crimean-Congo Hemorrhagic Fever Survivors Elicit Protective Non-Neutralizing Antibodies that Target 11 Overlapping Regions on Viral Glycoprotein GP38.
Shin OS, Monticelli SR, Hjorth CK, Hornet V, Doyle M, Abelson D, Kuehne AI, Wang A, Bakken RR, Mishra A, Middlecamp M, Champney E, Stuart L, Maurer DP, Li J, Berrigan J, Barajas J, Balinandi S, Lutwama JJ, Lobel L, Zeitlin L, Walker LM, Dye JM, Chandran K, Herbert AS, Pauli NT, McLellan JS. Shin OS, et al. Among authors: mclellan js. bioRxiv [Preprint]. 2024 Mar 6:2024.03.02.583110. doi: 10.1101/2024.03.02.583110. bioRxiv. 2024. Update in: Cell Rep. 2024 Jul 23;43(7):114502. doi: 10.1016/j.celrep.2024.114502 PMID: 38496658 Free PMC article. Updated. Preprint.
Antibodies targeting Crimean-Congo hemorrhagic fever virus GP38 limit vascular leak and viral spread.
Pahmeier F, Monticelli SR, Feng X, Hjorth CK, Wang A, Kuehne AI, Bakken RR, Batchelor TG, Lee SE, Middlecamp M, Stuart L, Abelson DM, McLellan JS, Biering SB, Herbert AS, Chandran K, Harris E. Pahmeier F, et al. Among authors: mclellan js. bioRxiv [Preprint]. 2024 May 23:2024.05.23.595578. doi: 10.1101/2024.05.23.595578. bioRxiv. 2024. PMID: 38826290 Free PMC article. Preprint.
Distinct pathway for evolution of enhanced receptor binding and cell entry in SARS-like bat coronaviruses.
Tse AL, Acreman CM, Ricardo-Lax I, Berrigan J, Lasso G, Balogun T, Kearns FL, Casalino L, McClain GL, Chandran AM, Lemeunier C, Amaro RE, Rice CM, Jangra RK, McLellan JS, Chandran K, Miller EH. Tse AL, et al. Among authors: mclellan js. bioRxiv [Preprint]. 2024 Jul 13:2024.06.24.600393. doi: 10.1101/2024.06.24.600393. bioRxiv. 2024. Update in: PLoS Pathog. 2024 Nov 15;20(11):e1012704. doi: 10.1371/journal.ppat.1012704 PMID: 38979151 Free PMC article. Updated. Preprint.
Elicitation of broadly protective sarbecovirus immunity by receptor-binding domain nanoparticle vaccines.
Walls AC, Miranda MC, Pham MN, Schäfer A, Greaney A, Arunachalam PS, Navarro MJ, Tortorici MA, Rogers K, O'Connor MA, Shireff L, Ferrell DE, Brunette N, Kepl E, Bowen J, Zepeda SK, Starr T, Hsieh CL, Fiala B, Wrenn S, Pettie D, Sydeman C, Johnson M, Blackstone A, Ravichandran R, Ogohara C, Carter L, Tilles SW, Rappuoli R, O'Hagan DT, Van Der Most R, Van Voorhis WC, McLellan JS, Kleanthous H, Sheahan TP, Fuller DH, Villinger F, Bloom J, Pulendran B, Baric R, King N, Veesler D. Walls AC, et al. Among authors: mclellan js. bioRxiv [Preprint]. 2021 Mar 16:2021.03.15.435528. doi: 10.1101/2021.03.15.435528. bioRxiv. 2021. Update in: Cell. 2021 Oct 14;184(21):5432-5447.e16. doi: 10.1016/j.cell.2021.09.015 PMID: 33758839 Free PMC article. Updated. Preprint.
Early cross-coronavirus reactive signatures of protective humoral immunity against COVID-19.
Kaplonek P, Wang C, Bartsch Y, Fischinger S, Gorman MJ, Bowman K, Kang J, Dayal D, Martin P, Nowak R, Hsieh CL, Feldman J, Julg B, Nilles EJ, Musk ER, Menon AS, Fischer ES, McLellan JS, Schmidt A, Goldberg MB, Filbin M, Hacohen N, Lauffenburger DA, Alter G. Kaplonek P, et al. Among authors: mclellan js. bioRxiv [Preprint]. 2021 May 12:2021.05.11.443609. doi: 10.1101/2021.05.11.443609. bioRxiv. 2021. Update in: Sci Immunol. 2021 Oct 15;6(64):eabj2901. doi: 10.1126/sciimmunol.abj2901 PMID: 34013263 Free PMC article. Updated. Preprint.
Efficient discovery of potently neutralizing SARS-CoV-2 antibodies using LIBRA-seq with ligand blocking.
Shiakolas AR, Johnson N, Kramer KJ, Suryadevara N, Wrapp D, Periasamy S, Pilewski KA, Raju N, Nargi R, Sutton RE, Walker L, Setliff I, Crowe JE, Bukreyev A, Carnahan RH, McLellan JS, Georgiev IS. Shiakolas AR, et al. Among authors: mclellan js. bioRxiv [Preprint]. 2021 Jun 30:2021.06.02.446813. doi: 10.1101/2021.06.02.446813. bioRxiv. 2021. Update in: Nat Biotechnol. 2022 Aug;40(8):1270-1275. doi: 10.1038/s41587-022-01232-2 PMID: 34100018 Free PMC article. Updated. Preprint.
Discovery and Characterization of a Pan-betacoronavirus S2-binding antibody.
Johnson NV, Wall SC, Kramer KJ, Holt CM, Periasamy S, Richardson S, Suryadevara N, Andreano E, Paciello I, Pierleoni G, Piccini G, Huang Y, Ge P, Allen JD, Uno N, Shiakolas AR, Pilewski KA, Nargi RS, Sutton RE, Abu-Shmais AA, Parks R, Haynes BF, Carnahan RH, Crowe JE Jr, Montomoli E, Rappuoli R, Bukreyev A, Ross TM, Sautto GA, McLellan JS, Georgiev IS. Johnson NV, et al. Among authors: mclellan js. bioRxiv [Preprint]. 2024 Jan 16:2024.01.15.575741. doi: 10.1101/2024.01.15.575741. bioRxiv. 2024. Update in: Structure. 2024 Nov 7;32(11):1893-1909.e11. doi: 10.1016/j.str.2024.08.022 PMID: 38293237 Free PMC article. Updated. Preprint.
Hybrid immunity to SARS-CoV-2 arises from serological recall of IgG antibodies distinctly imprinted by infection or vaccination.
Voss WN, Mallory MA, Byrne PO, Marchioni JM, Knudson SA, Powers JM, Leist SR, Dadonaite B, Townsend DR, Kain J, Huang Y, Satterwhite E, Castillo IN, Mattocks M, Paresi C, Munt JE, Scobey T, Seeger A, Premkumar L, Bloom JD, Georgiou G, McLellan JS, Baric RS, Lavinder JJ, Ippolito GC. Voss WN, et al. Among authors: mclellan js. bioRxiv [Preprint]. 2024 Jan 23:2024.01.22.576742. doi: 10.1101/2024.01.22.576742. bioRxiv. 2024. Update in: Cell Rep Med. 2024 Aug 20;5(8):101668. doi: 10.1016/j.xcrm.2024.101668 PMID: 38545622 Free PMC article. Updated. Preprint.
218 results