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Towards the competent conformation for catalysis in the ferredoxin-NADP+ reductase from the Brucella ovis pathogen.
Pérez-Amigot D, Taleb V, Boneta S, Anoz-Carbonell E, Sebastián M, Velázquez-Campoy A, Polo V, Martínez-Júlvez M, Medina M. Pérez-Amigot D, et al. Among authors: medina m. Biochim Biophys Acta Bioenerg. 2019 Oct 1;1860(10):148058. doi: 10.1016/j.bbabio.2019.148058. Epub 2019 Aug 5. Biochim Biophys Acta Bioenerg. 2019. PMID: 31394095 Free article.
Structural basis of the pleiotropic and specific phenotypic consequences of missense mutations in the multifunctional NAD(P)H:quinone oxidoreductase 1 and their pharmacological rescue.
Pacheco-Garcia JL, Anoz-Carbonell E, Vankova P, Kannan A, Palomino-Morales R, Mesa-Torres N, Salido E, Man P, Medina M, Naganathan AN, Pey AL. Pacheco-Garcia JL, et al. Among authors: medina m. Redox Biol. 2021 Oct;46:102112. doi: 10.1016/j.redox.2021.102112. Epub 2021 Aug 18. Redox Biol. 2021. PMID: 34537677 Free PMC article.
Different phenotypic outcome due to site-specific phosphorylation in the cancer-associated NQO1 enzyme studied by phosphomimetic mutations.
Pacheco-Garcia JL, Anoz-Carbonell E, Loginov DS, Vankova P, Salido E, Man P, Medina M, Palomino-Morales R, Pey AL. Pacheco-Garcia JL, et al. Among authors: medina m. Arch Biochem Biophys. 2022 Oct 30;729:109392. doi: 10.1016/j.abb.2022.109392. Epub 2022 Sep 9. Arch Biochem Biophys. 2022. PMID: 36096178 Free article.
Beyond a platform protein for the degradosome assembly: The Apoptosis-Inducing Factor as an efficient nuclease involved in chromatinolysis.
Novo N, Romero-Tamayo S, Marcuello C, Boneta S, Blasco-Machin I, Velázquez-Campoy A, Villanueva R, Moreno-Loshuertos R, Lostao A, Medina M, Ferreira P. Novo N, et al. Among authors: medina m. PNAS Nexus. 2022 Dec 26;2(2):pgac312. doi: 10.1093/pnasnexus/pgac312. eCollection 2023 Feb. PNAS Nexus. 2022. PMID: 36845352 Free PMC article.
New insights into the function and molecular mechanisms of Ferredoxin-NADP+ reductase from Brucella ovis.
Moreno A, Quereda-Moraleda I, Lozano-Vallhonrat C, Buñuel-Escudero M, Botha S, Kupitz C, Lisova S, Sierra R, Mariani V, Schleissner P, Gee LB, Dörner K, Schmidt C, Han H, Kloos M, Smyth P, Valerio J, Schulz J, de Wijn R, Melo DVM, Round A, Trost F, Sobolev E, Juncheng E, Sikorski M, Bean R, Martínez-Júlvez M, Martin-Garcia JM, Medina M. Moreno A, et al. Among authors: medina m. Arch Biochem Biophys. 2024 Dec;762:110204. doi: 10.1016/j.abb.2024.110204. Epub 2024 Nov 8. Arch Biochem Biophys. 2024. PMID: 39522858 Free article.
2,065 results