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Page 1
Functionalization of Chlorotonils: Dehalogenil as Promising Lead Compound for In Vivo Application.
Hofer W, Deschner F, Jézéquel G, Pessanha de Carvalho L, Abdel-Wadood N, Pätzold L, Bernecker S, Morgenstern B, Kany AM, Große M, Stadler M, Bischoff M, Hirsch AKH, Held J, Herrmann J, Müller R. Hofer W, et al. Among authors: jezequel g. Angew Chem Int Ed Engl. 2024 May 6;63(19):e202319765. doi: 10.1002/anie.202319765. Epub 2024 Apr 3. Angew Chem Int Ed Engl. 2024. PMID: 38502093
Structure-Based Design of α-Substituted Mercaptoacetamides as Inhibitors of the Virulence Factor LasB from Pseudomonas aeruginosa.
Kaya C, Walter I, Alhayek A, Shafiei R, Jézéquel G, Andreas A, Konstantinović J, Schönauer E, Sikandar A, Haupenthal J, Müller R, Brandstetter H, Hartmann RW, Hirsch AKH. Kaya C, et al. Among authors: jezequel g. ACS Infect Dis. 2022 May 13;8(5):1010-1021. doi: 10.1021/acsinfecdis.1c00628. Epub 2022 Apr 22. ACS Infect Dis. 2022. PMID: 35451824 Free PMC article.
Minimalist Natural ORPphilin Macarangin B Delineates OSBP Biological Function.
Jézéquel G, Grimanelli Z, Guimard C, Bigay J, Haddad J, Bignon J, Apel C, Steinmetz V, Askenatzis L, Levaïque H, Pradelli C, Pham VC, Huong DTM, Litaudon M, Gautier R, El Kalamouni C, Antonny B, Desrat S, Mesmin B, Roussi F. Jézéquel G, et al. J Med Chem. 2024 Dec 20. doi: 10.1021/acs.jmedchem.4c01705. Online ahead of print. J Med Chem. 2024. PMID: 39704626
Structure-Based Design of a Lead Compound Derived from Natural Schweinfurthins with Antitumor Properties That Target Oxysterol-Binding Protein.
Jézéquel G, Rampal C, Guimard C, Kovacs D, Polidori J, Bigay J, Bignon J, Askenatzis L, Litaudon M, Pham VC, Huong DTM, Nguyen AL, Pruvost A, Virolle T, Mesmin B, Desrat S, Antonny B, Roussi F. Jézéquel G, et al. J Med Chem. 2023 Oct 26;66(20):14208-14220. doi: 10.1021/acs.jmedchem.3c01298. Epub 2023 Oct 5. J Med Chem. 2023. PMID: 37795600
Cytotoxic Prenylated Stilbenes Isolated from Macaranga tanarius.
Péresse T, Jézéquel G, Allard PM, Pham VC, Huong DTM, Blanchard F, Bignon J, Lévaique H, Wolfender JL, Litaudon M, Roussi F. Péresse T, et al. Among authors: jezequel g. J Nat Prod. 2017 Oct 27;80(10):2684-2691. doi: 10.1021/acs.jnatprod.7b00409. Epub 2017 Oct 3. J Nat Prod. 2017. PMID: 28972755
20 results