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Page 1
Prime, shock and kill: BCL-2 inhibition for HIV cure.
Chandrasekar AP, Badley AD. Chandrasekar AP, et al. Front Immunol. 2022 Oct 20;13:1033609. doi: 10.3389/fimmu.2022.1033609. eCollection 2022. Front Immunol. 2022. PMID: 36341439 Free PMC article. Review.
TRAILshort Protects against CD4 T Cell Death during Acute HIV Infection.
Natesampillai S, Paim AC, Cummins NW, Chandrasekar AP, Bren GD, Lewin SR, Kiem HP, Badley AD. Natesampillai S, et al. Among authors: chandrasekar ap. J Immunol. 2019 Aug 1;203(3):718-724. doi: 10.4049/jimmunol.1900271. Epub 2019 Jun 12. J Immunol. 2019. PMID: 31189571 Free PMC article.
Reactivating latent HIV with PKC agonists induces resistance to apoptosis and is associated with phosphorylation and activation of BCL2.
French AJ, Natesampillai S, Krogman A, Correia C, Peterson KL, Alto A, Chandrasekar AP, Misra A, Li Y, Kaufmann SH, Badley AD, Cummins NW. French AJ, et al. Among authors: chandrasekar ap. PLoS Pathog. 2020 Oct 19;16(10):e1008906. doi: 10.1371/journal.ppat.1008906. eCollection 2020 Oct. PLoS Pathog. 2020. PMID: 33075109 Free PMC article.
The BCL-2 Inhibitor Venetoclax Augments Immune Effector Function Mediated by Fas Ligand, TRAIL, and Perforin/Granzyme B, Resulting in Reduced Plasma Viremia and Decreased HIV Reservoir Size during Acute HIV Infection in a Humanized Mouse Model.
Chandrasekar AP, Cummins NW, Natesampillai S, Misra A, Alto A, Laird G, Badley AD. Chandrasekar AP, et al. J Virol. 2022 Dec 21;96(24):e0173022. doi: 10.1128/jvi.01730-22. Epub 2022 Nov 30. J Virol. 2022. PMID: 36448802 Free PMC article.
The long road to TRAIL therapy: a TRAILshort detour.
Chandrasekar AP, Maynes M, Badley AD. Chandrasekar AP, et al. Oncotarget. 2021 Mar 30;12(7):589-591. doi: 10.18632/oncotarget.27902. eCollection 2021 Mar 30. Oncotarget. 2021. PMID: 33868580 Free PMC article. No abstract available.
"It's Pink!".
Chandrasekar AP, Wang Q, Block DR. Chandrasekar AP, et al. Clin Chem. 2024 Mar 2;70(3):565-566. doi: 10.1093/clinchem/hvad226. Clin Chem. 2024. PMID: 38431274 No abstract available.