Luesch H - Search Results

1

Progress in the discovery and development of anticancer agents from marine cyanobacteria.

Luesch H, Ellis EK, Chen QY, Ratnayake R. Luesch H, et al. Nat Prod Rep. 2024 Dec 2. doi: 10.1039/d4np00019f. Online ahead of print. Nat Prod Rep. 2024. PMID: 39620500 Free PMC article. Review.

2

The Chemistry of Phytoplankton.

Liu X, Bian Z, Hu S, Dickinson CF, Benjamin MM, Jia J, Tian Y, Place A, Hanna GS, Luesch H, Croot P, Reddy MM, Thomas OP, Hardiman G, Puglisi MP, Yang M, Zhong Z, Lemasters JJ, Korte JE, Waters AL, Heltzel CE, Williamson RT, Strangman WK, Valeriote F, Tius MA, DiTullio GR, Ferreira D, Alekseyenko A, Wang S, Hamann MT, Wang X. Liu X, et al. Among authors: luesch h. Chem Rev. 2024 Dec 11;124(23):13099-13177. doi: 10.1021/acs.chemrev.4c00177. Epub 2024 Nov 21. Chem Rev. 2024. PMID: 39571071 Free PMC article. Review.

3

Probing a distinct druggable tubulin binding site with gatorbulins 1-7, their metabolic and physicochemical properties, and pharmacological consequences.

Chen QY, Ratnayake R, Hortigüela R, Seabra GM, Cameron MD, Fernando Díaz J, Ángela Oliva M, Luesch H. Chen QY, et al. Among authors: luesch h. Bioorg Med Chem. 2023 Oct 21;95:117506. doi: 10.1016/j.bmc.2023.117506. Online ahead of print. Bioorg Med Chem. 2023. PMID: 39492252 Free article.

4

Isolation and Characterization of the Cyanobacterial Macrolide Glycoside Moorenaside, an Anti-Inflammatory Analogue of Aurisides Targeting the Keap1/Nrf2 Pathway.

Al-Awadhi FH, Kokkaliari S, Ratnayake R, Paul VJ, Luesch H. Al-Awadhi FH, et al. Among authors: luesch h. J Nat Prod. 2024 Oct 25;87(10):2355-2365. doi: 10.1021/acs.jnatprod.4c00420. Epub 2024 Sep 24. J Nat Prod. 2024. PMID: 39315953 Free PMC article.

5

Small molecular weight epigenetic inhibitors modulate the extracellular matrix during pancreatic acinar ductal metaplasia.

Perkins CM, Mao Y, Jiang J, Wilkie DJ, Han B, Chen QY, Luesch H, Ali J, Schmittgen TD. Perkins CM, et al. Among authors: luesch h. Biochem Biophys Res Commun. 2024 Dec 3;736:150496. doi: 10.1016/j.bbrc.2024.150496. Epub 2024 Aug 3. Biochem Biophys Res Commun. 2024. PMID: 39128264 Free article.

6

Isolation, Structure Elucidation, and Biological Activity of the Selective TACR2 Antagonist Tumonolide and its Aldehyde from a Marine Cyanobacterium.

Kokkaliari S, Grauso L, Mangoni A, Seabra G, Paul VJ, Luesch H. Kokkaliari S, et al. Among authors: luesch h. Chemistry. 2024 Sep 5;30(50):e202401393. doi: 10.1002/chem.202401393. Epub 2024 Jul 18. Chemistry. 2024. PMID: 39023398

7

Morphological profiling for drug discovery in the era of deep learning.

Tang Q, Ratnayake R, Seabra G, Jiang Z, Fang R, Cui L, Ding Y, Kahveci T, Bian J, Li C, Luesch H, Li Y. Tang Q, et al. Among authors: luesch h. Brief Bioinform. 2024 May 23;25(4):bbae284. doi: 10.1093/bib/bbae284. Brief Bioinform. 2024. PMID: 38886164 Free PMC article. Review.

8

Chemical Genetics in C. elegans Identifies Anticancer Mycotoxins Chaetocin and Chetomin as Potent Inducers of a Nuclear Metal Homeostasis Response.

Abraham E, Athapaththu AMGK, Atanasova KR, Chen QY, Corcoran TJ, Piloto J, Wu CW, Ratnayake R, Luesch H, Choe KP. Abraham E, et al. Among authors: luesch h. ACS Chem Biol. 2024 May 17;19(5):1180-1193. doi: 10.1021/acschembio.4c00131. Epub 2024 Apr 23. ACS Chem Biol. 2024. PMID: 38652683

9

VCP/p97 mediates nuclear targeting of non-ER-imported prion protein to maintain proteostasis.

Banik P, Ray K, Kamps J, Chen QY, Luesch H, Winklhofer KF, Tatzelt J. Banik P, et al. Among authors: luesch h. Life Sci Alliance. 2024 Apr 3;7(6):e202302456. doi: 10.26508/lsa.202302456. Print 2024 Jun. Life Sci Alliance. 2024. PMID: 38570188 Free PMC article.

10

Epigenetic small-molecule screen for inhibition and reversal of acinar ductal metaplasia in mouse pancreatic organoids.

Atanasova KR, Perkins CM, Ratnayake R, Jiang J, Chen QY, Schmittgen TD, Luesch H. Atanasova KR, et al. Among authors: luesch h. Front Pharmacol. 2024 Mar 6;15:1335246. doi: 10.3389/fphar.2024.1335246. eCollection 2024. Front Pharmacol. 2024. PMID: 38510657 Free PMC article.

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