Harris SP - Search Results

1

Myosin-binding protein C regulates the sarcomere lattice and stabilizes the OFF states of myosin heads.

Hessel AL, Engels NM, Kuehn MN, Nissen D, Sadler RL, Ma W, Irving TC, Linke WA, Harris SP. Hessel AL, et al. Among authors: harris sp. Nat Commun. 2024 Mar 23;15(1):2628. doi: 10.1038/s41467-024-46957-7. Nat Commun. 2024. PMID: 38521794 Free PMC article.

2

Myosin-binding protein C forms C-links and stabilizes OFF states of myosin.

Hessel AL, Engels NM, Kuehn M, Nissen D, Sadler RL, Ma W, Irving TC, Linke WA, Harris SP. Hessel AL, et al. Among authors: harris sp. bioRxiv [Preprint]. 2023 Sep 12:2023.09.10.556972. doi: 10.1101/2023.09.10.556972. bioRxiv. 2023. PMID: 37745361 Free PMC article. Preprint.

3

Cryo-Electron Microscopy Reveals Cardiac Myosin Binding Protein-C M-Domain Interactions with the Thin Filament.

Risi CM, Villanueva E, Belknap B, Sadler RL, Harris SP, White HD, Galkin VE. Risi CM, et al. Among authors: harris sp. J Mol Biol. 2022 Dec 30;434(24):167879. doi: 10.1016/j.jmb.2022.167879. Epub 2022 Nov 10. J Mol Biol. 2022. PMID: 36370805 Free PMC article.

4

Earning stripes: myosin binding protein-C interactions with actin.

van Dijk SJ, Bezold KL, Harris SP. van Dijk SJ, et al. Among authors: harris sp. Pflugers Arch. 2014 Mar;466(3):445-50. doi: 10.1007/s00424-013-1432-8. Epub 2014 Jan 19. Pflugers Arch. 2014. PMID: 24442149 Free PMC article. Review.

5

Orientation of myosin binding protein C in the cardiac muscle sarcomere determined by domain-specific immuno-EM.

Lee K, Harris SP, Sadayappan S, Craig R. Lee K, et al. Among authors: harris sp. J Mol Biol. 2015 Jan 30;427(2):274-86. doi: 10.1016/j.jmb.2014.10.023. Epub 2014 Nov 6. J Mol Biol. 2015. PMID: 25451032 Free PMC article.

6

Point mutations in the tri-helix bundle of the M-domain of cardiac myosin binding protein-C influence systolic duration and delay cardiac relaxation.

van Dijk SJ, Kooiker KB, Napierski NC, Touma KD, Mazzalupo S, Harris SP. van Dijk SJ, et al. Among authors: harris sp. J Mol Cell Cardiol. 2018 Jun;119:116-124. doi: 10.1016/j.yjmcc.2018.05.001. Epub 2018 May 3. J Mol Cell Cardiol. 2018. PMID: 29729251 Free PMC article.

7

Normal cardiac contraction in mice lacking the proline-alanine rich region and C1 domain of cardiac myosin binding protein C.

van Dijk SJ, Witt CC, Harris SP. van Dijk SJ, et al. Among authors: harris sp. J Mol Cell Cardiol. 2015 Nov;88:124-32. doi: 10.1016/j.yjmcc.2015.09.006. Epub 2015 Oct 8. J Mol Cell Cardiol. 2015. PMID: 26455481 Free PMC article.

8

C0 and C1 N-terminal Ig domains of myosin binding protein C exert different effects on thin filament activation.

Harris SP, Belknap B, Van Sciver RE, White HD, Galkin VE. Harris SP, et al. Proc Natl Acad Sci U S A. 2016 Feb 9;113(6):1558-63. doi: 10.1073/pnas.1518891113. Epub 2016 Feb 1. Proc Natl Acad Sci U S A. 2016. PMID: 26831109 Free PMC article.

9

Ablation of cardiac myosin binding protein-C disrupts the super-relaxed state of myosin in murine cardiomyocytes.

McNamara JW, Li A, Smith NJ, Lal S, Graham RM, Kooiker KB, van Dijk SJ, Remedios CGD, Harris SP, Cooke R. McNamara JW, et al. Among authors: harris sp. J Mol Cell Cardiol. 2016 May;94:65-71. doi: 10.1016/j.yjmcc.2016.03.009. Epub 2016 Mar 26. J Mol Cell Cardiol. 2016. PMID: 27021517 Free PMC article.

10

N-Terminal Domains of Cardiac Myosin Binding Protein C Cooperatively Activate the Thin Filament.

Risi C, Belknap B, Forgacs-Lonart E, Harris SP, Schröder GF, White HD, Galkin VE. Risi C, et al. Among authors: harris sp. Structure. 2018 Dec 4;26(12):1604-1611.e4. doi: 10.1016/j.str.2018.08.007. Epub 2018 Sep 27. Structure. 2018. PMID: 30270174 Free PMC article.

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