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Page 1
Cyclin dependent kinase 4/6 inhibitor palbociclib synergizes with BCL2 inhibitor venetoclax in experimental models of mantle cell lymphoma without RB1 deletion.
Malarikova D, Jorda R, Kupcova K, Senavova J, Dolnikova A, Pokorna E, Kazantsev D, Nozickova K, Sovilj D, Bellanger C, Chiron D, Andera L, Krystof V, Strnad M, Helman K, Klanova M, Trneny M, Havranek O, Klener P. Malarikova D, et al. Among authors: krystof v. Exp Hematol Oncol. 2024 Mar 25;13(1):34. doi: 10.1186/s40164-024-00499-2. Exp Hematol Oncol. 2024. PMID: 38528594 Free PMC article.
Characterization of new highly selective pyrazolo[4,3-d]pyrimidine inhibitor of CDK7.
Kovalová M, Havlíček L, Djukic S, Škerlová J, Peřina M, Pospíšil T, Řezníčková E, Řezáčová P, Jorda R, Kryštof V. Kovalová M, et al. Among authors: krystof v. Biomed Pharmacother. 2023 May;161:114492. doi: 10.1016/j.biopha.2023.114492. Epub 2023 Mar 15. Biomed Pharmacother. 2023. PMID: 36931035 Free article.
A patent review of cyclin-dependent kinase 7 (CDK7) inhibitors (2018-2022).
Kovalová M, Baraka JP, Mik V, Jorda R, Luo L, Shao H, Kryštof V. Kovalová M, et al. Among authors: krystof v. Expert Opin Ther Pat. 2023 Feb;33(2):67-87. doi: 10.1080/13543776.2023.2195547. Epub 2023 Apr 10. Expert Opin Ther Pat. 2023. PMID: 36975020 Free article. Review.
Identification of furo[2,3-d]pyrimidin-4-ylsulfanyl-1,3,4-thiadiazole derivatives as novel FLT3-ITD inhibitors.
Moradi M, Mousavi A, Řezníčková E, Peytam F, Peřina M, Vojáčková V, Firoozpour L, Jorda R, Grúz J, Emamgholipour Z, Sadat-Ebrahimi SE, Kryštof V, Foroumadi A. Moradi M, et al. Among authors: krystof v. Eur J Med Chem. 2024 Dec 15;280:116962. doi: 10.1016/j.ejmech.2024.116962. Epub 2024 Oct 12. Eur J Med Chem. 2024. PMID: 39427515 Free article.
2,4-Diaryl-pyrimido[1,2-a]benzimidazole derivatives as novel anticancer agents endowed with potent anti-leukemia activity: Synthesis, biological evaluation and kinase profiling.
Shaldam MA, Hendrychová D, El-Haggar R, Vojáčková V, Majrashi TA, Elkaeed EB, Masurier N, Kryštof V, Tawfik HO, Eldehna WM. Shaldam MA, et al. Among authors: krystof v. Eur J Med Chem. 2023 Oct 5;258:115610. doi: 10.1016/j.ejmech.2023.115610. Epub 2023 Jun 27. Eur J Med Chem. 2023. PMID: 37437350
165 results