Scott-Hewitt N - Search Results

1

Microglial-derived C1q integrates into neuronal ribonucleoprotein complexes and impacts protein homeostasis in the aging brain.

Scott-Hewitt N, Mahoney M, Huang Y, Korte N, Yvanka de Soysa T, Wilton DK, Knorr E, Mastro K, Chang A, Zhang A, Melville D, Schenone M, Hartigan C, Stevens B. Scott-Hewitt N, et al. Cell. 2024 Aug 8;187(16):4193-4212.e24. doi: 10.1016/j.cell.2024.05.058. Epub 2024 Jun 27. Cell. 2024. PMID: 38942014 Free article.

2

CSMD1 regulates brain complement activity and circuit development.

Baum ML, Wilton DK, Fox RG, Carey A, Hsu YH, Hu R, Jäntti HJ, Fahey JB, Muthukumar AK, Salla N, Crotty W, Scott-Hewitt N, Bien E, Sabatini DA, Lanser TB, Frouin A, Gergits F, Håvik B, Gialeli C, Nacu E, Lage K, Blom AM, Eggan K, McCarroll SA, Johnson MB, Stevens B. Baum ML, et al. Among authors: scott hewitt n. Brain Behav Immun. 2024 Jul;119:317-332. doi: 10.1016/j.bbi.2024.03.041. Epub 2024 Mar 27. Brain Behav Immun. 2024. PMID: 38552925 Free article.

3

Convergent mechanisms of microglia-mediated synaptic dysfunction contribute to diverse neuropathological conditions.

Scott-Hewitt N, Huang Y, Stevens B. Scott-Hewitt N, et al. Ann N Y Acad Sci. 2023 Jul;1525(1):5-27. doi: 10.1111/nyas.15010. Epub 2023 Jun 5. Ann N Y Acad Sci. 2023. PMID: 37272510 Review.

4

Engulfed by Glia: Glial Pruning in Development, Function, and Injury across Species.

Raiders S, Han T, Scott-Hewitt N, Kucenas S, Lew D, Logan MA, Singhvi A. Raiders S, et al. Among authors: scott hewitt n. J Neurosci. 2021 Feb 3;41(5):823-833. doi: 10.1523/JNEUROSCI.1660-20.2020. Epub 2021 Jan 19. J Neurosci. 2021. PMID: 33468571 Free PMC article. Review.

5

Local externalization of phosphatidylserine mediates developmental synaptic pruning by microglia.

Scott-Hewitt N, Perrucci F, Morini R, Erreni M, Mahoney M, Witkowska A, Carey A, Faggiani E, Schuetz LT, Mason S, Tamborini M, Bizzotto M, Passoni L, Filipello F, Jahn R, Stevens B, Matteoli M. Scott-Hewitt N, et al. EMBO J. 2020 Aug 17;39(16):e105380. doi: 10.15252/embj.2020105380. Epub 2020 Jul 13. EMBO J. 2020. PMID: 32657463 Free PMC article.

6

Heterozygous carriers of galactocerebrosidase mutations that cause Krabbe disease have impaired microglial function and defective repair of myelin damage.

Scott-Hewitt NJ, Folts CJ, Noble MD. Scott-Hewitt NJ, et al. Neural Regen Res. 2018 Mar;13(3):393-401. doi: 10.4103/1673-5374.228712. Neural Regen Res. 2018. PMID: 29623914 Free PMC article. Review.

7

Heterozygote galactocerebrosidase (GALC) mutants have reduced remyelination and impaired myelin debris clearance following demyelinating injury.

Scott-Hewitt NJ, Folts CJ, Hogestyn JM, Piester G, Mayer-Pröschel M, Noble MD. Scott-Hewitt NJ, et al. Hum Mol Genet. 2017 Aug 1;26(15):2825-2837. doi: 10.1093/hmg/ddx153. Hum Mol Genet. 2017. PMID: 28575206 Free PMC article.

8

Lysosomal Re-acidification Prevents Lysosphingolipid-Induced Lysosomal Impairment and Cellular Toxicity.

Folts CJ, Scott-Hewitt N, Pröschel C, Mayer-Pröschel M, Noble M. Folts CJ, et al. Among authors: scott hewitt n. PLoS Biol. 2016 Dec 15;14(12):e1002583. doi: 10.1371/journal.pbio.1002583. eCollection 2016 Dec. PLoS Biol. 2016. PMID: 27977664 Free PMC article.

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