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Interleukin-1 receptor accessory protein blockade limits the development of atherosclerosis and reduces plaque inflammation.
Mulholland M, Depuydt MAC, Jakobsson G, Ljungcrantz I, Grentzmann A, To F, Bengtsson E, Jaensson Gyllenbäck E, Grönberg C, Rattik S, Liberg D, Schiopu A, Björkbacka H, Kuiper J, Bot I, Slütter B, Engelbertsen D. Mulholland M, et al. Among authors: jakobsson g. Cardiovasc Res. 2024 May 7;120(6):581-595. doi: 10.1093/cvr/cvae046. Cardiovasc Res. 2024. PMID: 38563353 Free PMC article.
Transcriptional Profiling and Functional Analysis of N1/N2 Neutrophils Reveal an Immunomodulatory Effect of S100A9-Blockade on the Pro-Inflammatory N1 Subpopulation.
Mihaila AC, Ciortan L, Macarie RD, Vadana M, Cecoltan S, Preda MB, Hudita A, Gan AM, Jakobsson G, Tucureanu MM, Barbu E, Balanescu S, Simionescu M, Schiopu A, Butoi E. Mihaila AC, et al. Among authors: jakobsson g. Front Immunol. 2021 Aug 10;12:708770. doi: 10.3389/fimmu.2021.708770. eCollection 2021. Front Immunol. 2021. PMID: 34447377 Free PMC article.
Vascular smooth muscle-specific YAP/TAZ deletion triggers aneurysm development in mouse aorta.
Arévalo Martínez M, Ritsvall O, Bastrup JA, Celik S, Jakobsson G, Daoud F, Winqvist C, Aspberg A, Rippe C, Maegdefessel L, Schiopu A, Jepps TA, Holmberg J, Swärd K, Albinsson S. Arévalo Martínez M, et al. Among authors: jakobsson g. JCI Insight. 2023 Sep 8;8(17):e170845. doi: 10.1172/jci.insight.170845. JCI Insight. 2023. PMID: 37561588 Free PMC article.
Therapeutic S100A8/A9 blockade inhibits myocardial and systemic inflammation and mitigates sepsis-induced myocardial dysfunction.
Jakobsson G, Papareddy P, Andersson H, Mulholland M, Bhongir R, Ljungcrantz I, Engelbertsen D, Björkbacka H, Nilsson J, Manea A, Herwald H, Ruiz-Meana M, Rodríguez-Sinovas A, Chew M, Schiopu A. Jakobsson G, et al. Crit Care. 2023 Sep 29;27(1):374. doi: 10.1186/s13054-023-04652-x. Crit Care. 2023. PMID: 37773186 Free PMC article.
Short-term S100A8/A9 Blockade Promotes Cardiac Neovascularization after Myocardial Infarction.
Mares RG, Suica VI, Uyy E, Boteanu RM, Ivan L, Cocuz IG, Sabau AH, Yadav V, Szabo IA, Cotoi OS, Tomut ME, Jakobsson G, Simionescu M, Antohe F, Schiopu A. Mares RG, et al. Among authors: jakobsson g. J Cardiovasc Transl Res. 2024 Dec;17(6):1389-1399. doi: 10.1007/s12265-024-10542-6. Epub 2024 Jul 15. J Cardiovasc Transl Res. 2024. PMID: 39009944 Free PMC article.
IL1RAP Blockade With a Monoclonal Antibody Reduces Cardiac Inflammation and Preserves Heart Function in Viral and Autoimmune Myocarditis.
Lema DA, Jakobsson G, Daoud A, Elias D, Talor MV, Rattik S, Grönberg C, Kalinoski H, Jaensson Gyllenbäck E, Wang N, Liberg D, Schiopu A, Čiháková D. Lema DA, et al. Among authors: jakobsson g. Circ Heart Fail. 2024 Dec;17(12):e011729. doi: 10.1161/CIRCHEARTFAILURE.124.011729. Epub 2024 Nov 8. Circ Heart Fail. 2024. PMID: 39513273 Free PMC article.
46 results