Brink R - Search Results

1

Inhibition of MERTK reduces organ fibrosis in mouse models of fibrotic disease.

Pan Z, El Sharkway R, Bayoumi A, Metwally M, Gloss BS, Brink R, Lu DB, Liddle C, Alqahtani SA, Yu J, O'Connell PJ, George J, Eslam M. Pan Z, et al. Among authors: brink r. Sci Transl Med. 2024 Apr 3;16(741):eadj0133. doi: 10.1126/scitranslmed.adj0133. Epub 2024 Apr 3. Sci Transl Med. 2024. PMID: 38569018

2

Nuclear factor κB-inducing kinase activation as a mechanism of pancreatic β cell failure in obesity.

Malle EK, Zammit NW, Walters SN, Koay YC, Wu J, Tan BM, Villanueva JE, Brink R, Loudovaris T, Cantley J, McAlpine SR, Hesselson D, Grey ST. Malle EK, et al. Among authors: brink r. J Exp Med. 2015 Jul 27;212(8):1239-54. doi: 10.1084/jem.20150218. Epub 2015 Jun 29. J Exp Med. 2015. PMID: 26122662 Free PMC article.

3

GPR65 inhibits experimental autoimmune encephalomyelitis through CD4⁺ T cell independent mechanisms that include effects on iNKT cells.

Wirasinha RC, Vijayan D, Smith NJ, Parnell GP, Swarbrick A, Brink R, King C, Stewart G, Booth DR, Batten M. Wirasinha RC, et al. Among authors: brink r. Immunol Cell Biol. 2018 Feb;96(2):128-136. doi: 10.1111/imcb.1031. Epub 2017 Dec 19. Immunol Cell Biol. 2018. PMID: 29363187

4

B cell-intrinsic signaling through IL-21 receptor and STAT3 is required for establishing long-lived antibody responses in humans.

Avery DT, Deenick EK, Ma CS, Suryani S, Simpson N, Chew GY, Chan TD, Palendira U, Bustamante J, Boisson-Dupuis S, Choo S, Bleasel KE, Peake J, King C, French MA, Engelhard D, Al-Hajjar S, Al-Muhsen S, Magdorf K, Roesler J, Arkwright PD, Hissaria P, Riminton DS, Wong M, Brink R, Fulcher DA, Casanova JL, Cook MC, Tangye SG. Avery DT, et al. Among authors: brink r. J Exp Med. 2010 Jan 18;207(1):155-71. doi: 10.1084/jem.20091706. Epub 2010 Jan 4. J Exp Med. 2010. PMID: 20048285 Free PMC article.

5

Antigen-affinity controls pre-germinal center B cell selection by promoting Mcl-1 induction through BAFF receptor signaling.

Wensveen FM, Slinger E, van Attekum MH, Brink R, Eldering E. Wensveen FM, et al. Among authors: brink r. Sci Rep. 2016 Oct 20;6:35673. doi: 10.1038/srep35673. Sci Rep. 2016. PMID: 27762293 Free PMC article.

6

In vivo control of B-cell survival and antigen-specific B-cell responses.

Chan TD, Gardam S, Gatto D, Turner VM, Silke J, Brink R. Chan TD, et al. Among authors: brink r. Immunol Rev. 2010 Sep;237(1):90-103. doi: 10.1111/j.1600-065X.2010.00942.x. Immunol Rev. 2010. PMID: 20727031 Review.

7

Deletion of cIAP1 and cIAP2 in murine B lymphocytes constitutively activates cell survival pathways and inactivates the germinal center response.

Gardam S, Turner VM, Anderton H, Limaye S, Basten A, Koentgen F, Vaux DL, Silke J, Brink R. Gardam S, et al. Among authors: brink r. Blood. 2011 Apr 14;117(15):4041-51. doi: 10.1182/blood-2010-10-312793. Epub 2011 Feb 7. Blood. 2011. PMID: 21300983 Free article.

8

Non-Canonical NF-κB Signaling Initiated by BAFF Influences B Cell Biology at Multiple Junctures.

Gardam S, Brink R. Gardam S, et al. Among authors: brink r. Front Immunol. 2014 Jan 6;4:509. doi: 10.3389/fimmu.2013.00509. eCollection 2014 Jan 6. Front Immunol. 2014. PMID: 24432023 Free PMC article. Review.

9

Myeloid cell TRAF3 promotes metabolic inflammation, insulin resistance, and hepatic steatosis in obesity.

Chen Z, Shen H, Sun C, Yin L, Tang F, Zheng P, Liu Y, Brink R, Rui L. Chen Z, et al. Among authors: brink r. Am J Physiol Endocrinol Metab. 2015 Mar 15;308(6):E460-9. doi: 10.1152/ajpendo.00470.2014. Epub 2015 Jan 27. Am J Physiol Endocrinol Metab. 2015. PMID: 25628422 Free PMC article.

10

IL-27 Directly Enhances Germinal Center B Cell Activity and Potentiates Lupus in Sanroque Mice.

Vijayan D, Mohd Redzwan N, Avery DT, Wirasinha RC, Brink R, Walters G, Adelstein S, Kobayashi M, Gray P, Elliott M, Wong M, King C, Vinuesa CG, Ghilardi N, Ma CS, Tangye SG, Batten M. Vijayan D, et al. Among authors: brink r. J Immunol. 2016 Oct 15;197(8):3008-3017. doi: 10.4049/jimmunol.1600652. Epub 2016 Sep 12. J Immunol. 2016. PMID: 27619997

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