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Pharmacological blockade of 2-AG degradation ameliorates clinical, neuroinflammatory and synaptic alterations in experimental autoimmune encephalomyelitis.
Guadalupi L, Mandolesi G, Vanni V, Balletta S, Caioli S, Pavlovic A, De Vito F, Fresegna D, Sanna K, Vitiello L, Nencini M, Tartacca A, Mariani F, Rovella V, Schippling S, Ruf I, Collin L, Centonze D, Musella A. Guadalupi L, et al. Among authors: de vito f. Neuropharmacology. 2024 Jul 1;252:109940. doi: 10.1016/j.neuropharm.2024.109940. Epub 2024 Apr 2. Neuropharmacology. 2024. PMID: 38570068 Free article.
Synaptopathy connects inflammation and neurodegeneration in multiple sclerosis.
Mandolesi G, Gentile A, Musella A, Fresegna D, De Vito F, Bullitta S, Sepman H, Marfia GA, Centonze D. Mandolesi G, et al. Among authors: de vito f. Nat Rev Neurol. 2015 Dec;11(12):711-24. doi: 10.1038/nrneurol.2015.222. Epub 2015 Nov 20. Nat Rev Neurol. 2015. PMID: 26585978 Review.
Siponimod (BAF312) prevents synaptic neurodegeneration in experimental multiple sclerosis.
Gentile A, Musella A, Bullitta S, Fresegna D, De Vito F, Fantozzi R, Piras E, Gargano F, Borsellino G, Battistini L, Schubart A, Mandolesi G, Centonze D. Gentile A, et al. Among authors: de vito f. J Neuroinflammation. 2016 Aug 26;13(1):207. doi: 10.1186/s12974-016-0686-4. J Neuroinflammation. 2016. PMID: 27566665 Free PMC article.
102 results