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Next Directions in the Neuroscience of Cancers Arising outside the CNS.
Amit M, Anastasaki C, Dantzer R, Demir IE, Deneen B, Dixon KO, Egeblad M, Gibson EM, Hervey-Jumper SL, Hondermarck H, Magnon C, Monje M, Na'ara S, Pan Y, Repasky EA, Scheff NN, Sloan EK, Talbot S, Tracey KJ, Trotman LC, Valiente M, Van Aelst L, Venkataramani V, Venkatesh HS, Vermeer PD, Winkler F, Wong RJ, Gutmann DH, Borniger JC. Amit M, et al. Among authors: trotman lc. Cancer Discov. 2024 Apr 4;14(4):669-673. doi: 10.1158/2159-8290.CD-23-1495. Cancer Discov. 2024. PMID: 38571430
Turning off AKT: PHLPP as a drug target.
Newton AC, Trotman LC. Newton AC, et al. Among authors: trotman lc. Annu Rev Pharmacol Toxicol. 2014;54:537-58. doi: 10.1146/annurev-pharmtox-011112-140338. Annu Rev Pharmacol Toxicol. 2014. PMID: 24392697 Free PMC article. Review.
The nuclear transport receptor Importin-11 is a tumor suppressor that maintains PTEN protein.
Chen M, Nowak DG, Narula N, Robinson B, Watrud K, Ambrico A, Herzka TM, Zeeman ME, Minderer M, Zheng W, Ebbesen SH, Plafker KS, Stahlhut C, Wang VM, Wills L, Nasar A, Castillo-Martin M, Cordon-Cardo C, Wilkinson JE, Powers S, Sordella R, Altorki NK, Mittal V, Stiles BM, Plafker SM, Trotman LC. Chen M, et al. Among authors: trotman lc. J Cell Biol. 2017 Mar 6;216(3):641-656. doi: 10.1083/jcb.201604025. Epub 2017 Feb 13. J Cell Biol. 2017. PMID: 28193700 Free PMC article.
Roadmap for the Emerging Field of Cancer Neuroscience.
Monje M, Borniger JC, D'Silva NJ, Deneen B, Dirks PB, Fattahi F, Frenette PS, Garzia L, Gutmann DH, Hanahan D, Hervey-Jumper SL, Hondermarck H, Hurov JB, Kepecs A, Knox SM, Lloyd AC, Magnon C, Saloman JL, Segal RA, Sloan EK, Sun X, Taylor MD, Tracey KJ, Trotman LC, Tuveson DA, Wang TC, White RA, Winkler F. Monje M, et al. Among authors: trotman lc. Cell. 2020 Apr 16;181(2):219-222. doi: 10.1016/j.cell.2020.03.034. Cell. 2020. PMID: 32302564 Free PMC article.
MYC Drives Pten/Trp53-Deficient Proliferation and Metastasis due to IL6 Secretion and AKT Suppression via PHLPP2.
Nowak DG, Cho H, Herzka T, Watrud K, DeMarco DV, Wang VM, Senturk S, Fellmann C, Ding D, Beinortas T, Kleinman D, Chen M, Sordella R, Wilkinson JE, Castillo-Martin M, Cordon-Cardo C, Robinson BD, Trotman LC. Nowak DG, et al. Among authors: trotman lc. Cancer Discov. 2015 Jun;5(6):636-51. doi: 10.1158/2159-8290.CD-14-1113. Epub 2015 Mar 31. Cancer Discov. 2015. PMID: 25829425 Free PMC article.
PTEN and p53: who will get the upper hand?
Trotman LC, Pandolfi PP. Trotman LC, et al. Cancer Cell. 2003 Feb;3(2):97-9. doi: 10.1016/s1535-6108(03)00022-9. Cancer Cell. 2003. PMID: 12620402 Free article. No abstract available.
New views into the prostate cancer genome.
Trotman L, Powers S. Trotman L, et al. Cancer Cell. 2010 Jul 13;18(1):1-2. doi: 10.1016/j.ccr.2010.06.011. Cancer Cell. 2010. PMID: 20609345 Free article.
Identification of PHLPP1 as a tumor suppressor reveals the role of feedback activation in PTEN-mutant prostate cancer progression.
Chen M, Pratt CP, Zeeman ME, Schultz N, Taylor BS, O'Neill A, Castillo-Martin M, Nowak DG, Naguib A, Grace DM, Murn J, Navin N, Atwal GS, Sander C, Gerald WL, Cordon-Cardo C, Newton AC, Carver BS, Trotman LC. Chen M, et al. Among authors: trotman lc. Cancer Cell. 2011 Aug 16;20(2):173-86. doi: 10.1016/j.ccr.2011.07.013. Cancer Cell. 2011. PMID: 21840483 Free PMC article.
54 results