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Synaptic injury in the inner plexiform layer of the retina is associated with progression in multiple sclerosis.
Cordano C, Werneburg S, Abdelhak A, Bennett DJ, Beaudry-Richard A, Duncan GJ, Oertel FC, Boscardin WJ, Yiu HH, Jabassini N, Merritt L, Nocera S, Sin JH, Samana IP, Condor Montes SY, Ananth K, Bischof A; UCSF MS EPIC Team; Nourbakhsh B, Hauser SL, Cree BAC, Emery B, Schafer DP, Chan JR, Green AJ. Cordano C, et al. Among authors: chan jr. Cell Rep Med. 2024 Apr 16;5(4):101490. doi: 10.1016/j.xcrm.2024.101490. Epub 2024 Apr 3. Cell Rep Med. 2024. PMID: 38574736 Free PMC article.
Identification and In Vivo Evaluation of Myelination Agent PIPE-3297, a Selective Kappa Opioid Receptor Agonist Devoid of β-Arrestin-2 Recruitment Efficacy.
Schrader TO, Lorrain KI, Bagnol D, Edu GC, Broadhead A, Baccei C, Poon MM, Stebbins KJ, Xiong Y, Lorenzana AO, Chan JR, Green AJ, Lorrain DS, Chen A. Schrader TO, et al. Among authors: chan jr. ACS Chem Neurosci. 2024 Feb 7;15(3):685-698. doi: 10.1021/acschemneuro.3c00807. Epub 2024 Jan 24. ACS Chem Neurosci. 2024. PMID: 38265210
Targeting the muscarinic M1 receptor with a selective, brain-penetrant antagonist to promote remyelination in multiple sclerosis.
Poon MM, Lorrain KI, Stebbins KJ, Edu GC, Broadhead AR, Lorenzana AJ, Roppe JR, Baccei JM, Baccei CS, Chen AC, Green AJ, Lorrain DS, Chan JR. Poon MM, et al. Among authors: chan jr. Proc Natl Acad Sci U S A. 2024 Aug 6;121(32):e2407974121. doi: 10.1073/pnas.2407974121. Epub 2024 Jul 31. Proc Natl Acad Sci U S A. 2024. PMID: 39083422 Free PMC article.
138 results