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Adaptive functions of structural variants in human brain development.
Ding W, Li X, Zhang J, Ji M, Zhang M, Zhong X, Cao Y, Liu X, Li C, Xiao C, Wang J, Li T, Yu Q, Mo F, Zhang B, Qi J, Yang JC, Qi J, Tian L, Xu X, Peng Q, Zhou WZ, Liu Z, Fu A, Zhang X, Zhang JJ, Sun Y, Hu B, An NA, Zhang L, Li CY. Ding W, et al. Among authors: an na. Sci Adv. 2024 Apr 5;10(14):eadl4600. doi: 10.1126/sciadv.adl4600. Epub 2024 Apr 5. Sci Adv. 2024. PMID: 38579006 Free PMC article.
Human exonization through differential nucleosome occupancy.
Li Y, Li C, Li S, Peng Q, An NA, He A, Li CY. Li Y, et al. Among authors: an na. Proc Natl Acad Sci U S A. 2018 Aug 28;115(35):8817-8822. doi: 10.1073/pnas.1802561115. Epub 2018 Aug 13. Proc Natl Acad Sci U S A. 2018. PMID: 30104384 Free PMC article.
A Human-Specific De Novo Gene Promotes Cortical Expansion and Folding.
Qi J, Mo F, An NA, Mi T, Wang J, Qi JT, Li X, Zhang B, Xia L, Lu Y, Sun G, Wang X, Li CY, Hu B. Qi J, et al. Among authors: an na. Adv Sci (Weinh). 2023 Mar;10(7):e2204140. doi: 10.1002/advs.202204140. Epub 2023 Jan 13. Adv Sci (Weinh). 2023. PMID: 36638273 Free PMC article.
Mechanistically, SP0535 interacts with the membrane protein Na(+) /K(+) ATPase subunit alpha-1 (ATP1A1) and releases Src from the ATP1A1-Src complex, allowing increased level of Src phosphorylation that promotes cell proliferation. Thus, SP0535 is the first proven human-sp …
Mechanistically, SP0535 interacts with the membrane protein Na(+) /K(+) ATPase subunit alpha-1 (ATP1A1) and releases Src from the ATP …
Origin of functional de novo genes in humans from "hopeful monsters".
Liu X, Xiao C, Xu X, Zhang J, Mo F, Chen JY, Delihas N, Zhang L, An NA, Li CY. Liu X, et al. Among authors: an na. Wiley Interdiscip Rev RNA. 2024 Mar-Apr;15(2):e1845. doi: 10.1002/wrna.1845. Wiley Interdiscip Rev RNA. 2024. PMID: 38605485 Review.
369 results