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Integrating system biology and intratumor gene therapy by trans-complementing the appropriate co-stimulatory molecule as payload in oncolytic herpes virus.
Finizio A, Pagano P, Napolano A, Froechlich G, Infante L, De Chiara A, Amiranda S, Vitiello E, Totaro S, Capasso C, Raia M, D'Alise AM, de Candia P, Zambrano N, Sasso E. Finizio A, et al. Among authors: froechlich g. Cancer Gene Ther. 2024 Sep;31(9):1335-1343. doi: 10.1038/s41417-024-00790-8. Epub 2024 Jun 5. Cancer Gene Ther. 2024. PMID: 38839891 Free PMC article.
Prime and pull of T cell responses against cancer-exogenous antigens is effective against CPI-resistant tumors.
Troise F, Leoni G, Sasso E, Del Sorbo M, Esposito M, Romano G, Allocca S, Froechlich G, Cotugno G, Capone S, Folgori A, Scarselli E, D'Alise AM, Nicosia A. Troise F, et al. Among authors: froechlich g. Mol Ther Oncol. 2024 Jan 10;32(1):200760. doi: 10.1016/j.omton.2024.200760. eCollection 2024 Mar 21. Mol Ther Oncol. 2024. PMID: 38596303 Free PMC article.
Integrity of the Antiviral STING-mediated DNA Sensing in Tumor Cells Is Required to Sustain the Immunotherapeutic Efficacy of Herpes Simplex Oncolytic Virus.
Froechlich G, Caiazza C, Gentile C, D'Alise AM, De Lucia M, Langone F, Leoni G, Cotugno G, Scisciola V, Nicosia A, Scarselli E, Mallardo M, Sasso E, Zambrano N. Froechlich G, et al. Cancers (Basel). 2020 Nov 17;12(11):3407. doi: 10.3390/cancers12113407. Cancers (Basel). 2020. PMID: 33213060 Free PMC article.
17 results