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HOIL1 mediates MDA5 activation through ubiquitination of LGP2.
Cheng D, Zhu J, Liu G, Gack MU, MacDuff DA. Cheng D, et al. Among authors: liu g. bioRxiv [Preprint]. 2024 Apr 3:2024.04.02.587772. doi: 10.1101/2024.04.02.587772. bioRxiv. 2024. PMID: 38617308 Free PMC article. Preprint.
Dysregulation of type I interferon responses in COVID-19.
Acharya D, Liu G, Gack MU. Acharya D, et al. Among authors: liu g. Nat Rev Immunol. 2020 Jul;20(7):397-398. doi: 10.1038/s41577-020-0346-x. Epub 2020 May 26. Nat Rev Immunol. 2020. PMID: 32457522 Free PMC article.
ISG15-dependent Activation of the RNA Sensor MDA5 and its Antagonism by the SARS-CoV-2 papain-like protease.
Liu G, Lee JH, Parker ZM, Acharya D, Chiang JJ, van Gent M, Riedl W, Davis-Gardner ME, Wies E, Chiang C, Gack MU. Liu G, et al. bioRxiv [Preprint]. 2020 Oct 27:2020.10.26.356048. doi: 10.1101/2020.10.26.356048. bioRxiv. 2020. Update in: Nat Microbiol. 2021 Apr;6(4):467-478. doi: 10.1038/s41564-021-00884-1 PMID: 33140045 Free PMC article. Updated. Preprint.
Mutations derived from horseshoe bat ACE2 orthologs enhance ACE2-Fc neutralization of SARS-CoV-2.
Mou H, Quinlan BD, Peng H, Liu G, Guo Y, Peng S, Zhang L, Davis-Gardner ME, Gardner MR, Crynen G, DeVaux LB, Voo ZX, Bailey CC, Alpert MD, Rader C, Gack MU, Choe H, Farzan M. Mou H, et al. Among authors: liu g. PLoS Pathog. 2021 Apr 9;17(4):e1009501. doi: 10.1371/journal.ppat.1009501. eCollection 2021 Apr. PLoS Pathog. 2021. PMID: 33836016 Free PMC article.
Actin cytoskeleton remodeling primes RIG-I-like receptor activation.
Acharya D, Reis R, Volcic M, Liu G, Wang MK, Chia BS, Nchioua R, Groß R, Münch J, Kirchhoff F, Sparrer KMJ, Gack MU. Acharya D, et al. Among authors: liu g. Cell. 2022 Sep 15;185(19):3588-3602.e21. doi: 10.1016/j.cell.2022.08.011. Cell. 2022. PMID: 36113429 Free PMC article.
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