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Ontology-based modeling, integration, and analysis of heterogeneous clinical, pathological, and molecular kidney data for precision medicine.
He YO, Barisoni L, Rosenberg AZ, Robinson PN, Diehl AD, Chen Y, Phuong JP, Hansen J, Herr BW, Börner K, Schaub J, Bonevich N, Arnous G, Boddapati S, Zheng J, Alakwaa F, Sarder P, Duncan WD, Liang C, Valerius MT, Jain S, Iyengar R, Himmelfarb J, Kretzler M; Kidney Precision Medicine Project. He YO, et al. Among authors: barisoni l. bioRxiv [Preprint]. 2024 Aug 4:2024.04.01.587658. doi: 10.1101/2024.04.01.587658. bioRxiv. 2024. PMID: 38617362 Free PMC article. Preprint.
Pegunigalsidase alfa, a novel PEGylated enzyme replacement therapy for Fabry disease, provides sustained plasma concentrations and favorable pharmacodynamics: A 1-year Phase 1/2 clinical trial.
Schiffmann R, Goker-Alpan O, Holida M, Giraldo P, Barisoni L, Colvin RB, Jennette CJ, Maegawa G, Boyadjiev SA, Gonzalez D, Nicholls K, Tuffaha A, Atta MG, Rup B, Charney MR, Paz A, Szlaifer M, Alon S, Brill-Almon E, Chertkoff R, Hughes D. Schiffmann R, et al. Among authors: barisoni l. J Inherit Metab Dis. 2019 May;42(3):534-544. doi: 10.1002/jimd.12080. Epub 2019 Apr 8. J Inherit Metab Dis. 2019. PMID: 30834538 Clinical Trial.
Modelling kidney disease using ontology: insights from the Kidney Precision Medicine Project.
Ong E, Wang LL, Schaub J, O'Toole JF, Steck B, Rosenberg AZ, Dowd F, Hansen J, Barisoni L, Jain S, de Boer IH, Valerius MT, Waikar SS, Park C, Crawford DC, Alexandrov T, Anderton CR, Stoeckert C, Weng C, Diehl AD, Mungall CJ, Haendel M, Robinson PN, Himmelfarb J, Iyengar R, Kretzler M, Mooney S, He Y; Kidney Precision Medicine Project. Ong E, et al. Among authors: barisoni l. Nat Rev Nephrol. 2020 Nov;16(11):686-696. doi: 10.1038/s41581-020-00335-w. Epub 2020 Sep 16. Nat Rev Nephrol. 2020. PMID: 32939051 Free PMC article. Review.
A multimodal and integrated approach to interrogate human kidney biopsies with rigor and reproducibility: guidelines from the Kidney Precision Medicine Project.
El-Achkar TM, Eadon MT, Menon R, Lake BB, Sigdel TK, Alexandrov T, Parikh S, Zhang G, Dobi D, Dunn KW, Otto EA, Anderton CR, Carson JM, Luo J, Park C, Hamidi H, Zhou J, Hoover P, Schroeder A, Joanes M, Azeloglu EU, Sealfon R, Winfree S, Steck B, He Y, D'Agati V, Iyengar R, Troyanskaya OG, Barisoni L, Gaut J, Zhang K, Laszik Z, Rovin BH, Dagher PC, Sharma K, Sarwal MM, Hodgin JB, Alpers CE, Kretzler M, Jain S. El-Achkar TM, et al. Among authors: barisoni l. Physiol Genomics. 2021 Jan 1;53(1):1-11. doi: 10.1152/physiolgenomics.00104.2020. Epub 2020 Nov 16. Physiol Genomics. 2021. PMID: 33197228 Free PMC article.
Integrating Patient Priorities with Science by Community Engagement in the Kidney Precision Medicine Project.
Tuttle KR, Knight R, Appelbaum PS, Arora T, Bansal S, Bebiak J, Brown K, Campbell C, Cooperman L, Corona-Villalobos CP, Dighe A, de Boer IH, Hall DE, Jefferson N, Jolly S, Kermani A, Lee SC, Mehl K, Murugan R, Roberts GV, Rosas SE, Himmelfarb J, Miller RT; Kidney Precision Medicine Project. Tuttle KR, et al. Clin J Am Soc Nephrol. 2021 Apr 7;16(4):660-668. doi: 10.2215/CJN.10270620. Epub 2020 Nov 30. Clin J Am Soc Nephrol. 2021. PMID: 33257411 Free PMC article.
Large-scale, three-dimensional tissue cytometry of the human kidney: a complete and accessible pipeline.
Ferkowicz MJ, Winfree S, Sabo AR, Kamocka MM, Khochare S, Barwinska D, Eadon MT, Cheng YH, Phillips CL, Sutton TA, Kelly KJ, Dagher PC, El-Achkar TM, Dunn KW; Kidney Precision Medicine Project. Ferkowicz MJ, et al. Lab Invest. 2021 May;101(5):661-676. doi: 10.1038/s41374-020-00518-w. Epub 2021 Jan 6. Lab Invest. 2021. PMID: 33408350 Free PMC article.
Rationale and design of the Kidney Precision Medicine Project.
de Boer IH, Alpers CE, Azeloglu EU, Balis UGJ, Barasch JM, Barisoni L, Blank KN, Bomback AS, Brown K, Dagher PC, Dighe AL, Eadon MT, El-Achkar TM, Gaut JP, Hacohen N, He Y, Hodgin JB, Jain S, Kellum JA, Kiryluk K, Knight R, Laszik ZG, Lienczewski C, Mariani LH, McClelland RL, Menez S, Moledina DG, Mooney SD, O'Toole JF, Palevsky PM, Parikh CR, Poggio ED, Rosas SE, Rosengart MR, Sarwal MM, Schaub JA, Sedor JR, Sharma K, Steck B, Toto RD, Troyanskaya OG, Tuttle KR, Vazquez MA, Waikar SS, Williams K, Wilson FP, Zhang K, Iyengar R, Kretzler M, Himmelfarb J; Kidney Precision Medicine Project. de Boer IH, et al. Among authors: barisoni l. Kidney Int. 2021 Mar;99(3):498-510. doi: 10.1016/j.kint.2020.08.039. Kidney Int. 2021. PMID: 33637194 Free PMC article.
Patient perspectives and involvement in precision medicine research.
Tuttle KR, Bebiak J, Brown K, Campbell C, Dighe A, Hyashi L, Jefferson N, Roberts GV, Stutzke C, Knight R; Kidney Precision Medicine Project. Tuttle KR, et al. Kidney Int. 2021 Mar;99(3):511-514. doi: 10.1016/j.kint.2020.10.036. Kidney Int. 2021. PMID: 33637195
147 results