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109 results

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Page 1
Rebound growth of BRAF mutant pediatric glioma cells after MAPKi withdrawal is associated with MAPK reactivation and secretion of microglia-recruiting cytokines.
Kocher D, Cao L, Guiho R, Langhammer M, Lai YL, Becker P, Hamdi H, Friedel D, Selt F, Vonhören D, Zaman J, Valinciute G, Herter S, Picard D, Rettenmeier J, Maass KK, Pajtler KW, Remke M, von Deimling A, Pusch S, Pfister SM, Oehme I, Jones DTW, Halbach S, Brummer T, Martinez-Barbera JP, Witt O, Milde T, Sigaud R. Kocher D, et al. Among authors: martinez barbera jp. J Neurooncol. 2024 Jun;168(2):317-332. doi: 10.1007/s11060-024-04672-9. Epub 2024 Apr 17. J Neurooncol. 2024. PMID: 38630384 Free PMC article.
Recurrent adamantinomatous craniopharyngiomas show MAPK pathway activation, clonal evolution and rare TP53-loss-mediated malignant progression.
Apps JR, Gonzalez-Meljem JM, Guiho R, Pickles JC, Prince E, Schwalbe E, Joshi N, Stone TJ, Ogunbiyi O, Chalker J, Bassey A, Otto G, Davies R, Hughes D, Brandner S, Tan E, Lee V, Hayhurst C, Kline C, Castellano S, Hankinson T, Deutschbein T, Jacques TS, Martinez-Barbera JP. Apps JR, et al. Among authors: martinez barbera jp. Acta Neuropathol Commun. 2024 Aug 10;12(1):127. doi: 10.1186/s40478-024-01838-4. Acta Neuropathol Commun. 2024. PMID: 39127699 Free PMC article.
Author Correction: mTOR regulates MAPKAPK2 translation to control the senescence-associated secretory phenotype.
Herranz N, Gallage S, Mellone M, Wuestefeld T, Klotz S, Hanley CJ, Raguz S, Acosta JC, Innes AJ, Banito A, Georgilis A, Montoya A, Wolter K, Dharmalingam G, Faull P, Carroll T, Martínez-Barbera JP, Cutillas P, Reisinger F, Heikenwalder M, Miller RA, Withers D, Zender L, Thomas GJ, Gil J. Herranz N, et al. Among authors: martinez barbera jp. Nat Cell Biol. 2024 Jun;26(6):1019. doi: 10.1038/s41556-024-01443-6. Nat Cell Biol. 2024. PMID: 38778130 No abstract available.
Implications of cellular senescence in paediatric pituitary tumours.
Gonzalez-Meljem JM, Martinez-Barbera JP. Gonzalez-Meljem JM, et al. Among authors: martinez barbera jp. EBioMedicine. 2024 Jan;99:104905. doi: 10.1016/j.ebiom.2023.104905. Epub 2023 Dec 2. EBioMedicine. 2024. PMID: 38043401 Free PMC article. Review.
Conditional Pten inactivation in pituitary results in sex-specific prolactinoma formation.
Flores-Martínez Á, Ramos-Herrero VD, Barroso A, Moreno A, G-García ME, Venegas-Moreno E, Dios E, Martínez-Barberá JP, Luque RM, Soto-Moreno A, Cano DA. Flores-Martínez Á, et al. Among authors: martinez barbera jp. Biochim Biophys Acta Mol Basis Dis. 2025 Jan;1871(1):167543. doi: 10.1016/j.bbadis.2024.167543. Epub 2024 Oct 18. Biochim Biophys Acta Mol Basis Dis. 2025. PMID: 39428000
Unraveling the complexity of the senescence-associated secretory phenotype in adamantinomatous craniopharyngioma using multimodal machine learning analysis.
Prince EW, Apps JR, Jeang J, Chee K, Medlin S, Jackson EM, Dudley R, Limbrick D, Naftel R, Johnston J, Feldstein N, Prolo LM, Ginn K, Niazi T, Smith A, Kilburn L, Chern J, Leonard J, Lam S, Hersh DS, Gonzalez-Meljem JM, Amani V, Donson AM, Mitra SS, Bandopadhayay P, Martinez-Barbera JP, Hankinson TC. Prince EW, et al. Among authors: martinez barbera jp. Neuro Oncol. 2024 Jun 3;26(6):1109-1123. doi: 10.1093/neuonc/noae015. Neuro Oncol. 2024. PMID: 38334125
COPI vesicle formation and N-myristoylation are targetable vulnerabilities of senescent cells.
McHugh D, Sun B, Gutierrez-Muñoz C, Hernández-González F, Mellone M, Guiho R, Duran I, Pombo J, Pietrocola F, Birch J, Kallemeijn WW, Khadayate S, Dharmalingam G, Vernia S, Tate EW, Martínez-Barbera JP, Withers DJ, Thomas GJ, Serrano M, Gil J. McHugh D, et al. Among authors: martinez barbera jp. Nat Cell Biol. 2023 Dec;25(12):1804-1820. doi: 10.1038/s41556-023-01287-6. Epub 2023 Nov 27. Nat Cell Biol. 2023. PMID: 38012402 Free PMC article.
Clearance of senescent macrophages ameliorates tumorigenesis in KRAS-driven lung cancer.
Haston S, Gonzalez-Gualda E, Morsli S, Ge J, Reen V, Calderwood A, Moutsopoulos I, Panousopoulos L, Deletic P, Carreno G, Guiho R, Manshaei S, Gonzalez-Meljem JM, Lim HY, Simpson DJ, Birch J, Pallikonda HA, Chandra T, Macias D, Doherty GJ, Rassl DM, Rintoul RC, Signore M, Mohorianu I, Akbar AN, Gil J, Muñoz-Espín D, Martinez-Barbera JP. Haston S, et al. Among authors: martinez barbera jp. Cancer Cell. 2023 Jul 10;41(7):1242-1260.e6. doi: 10.1016/j.ccell.2023.05.004. Epub 2023 Jun 1. Cancer Cell. 2023. PMID: 37267953 Free article.
109 results