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Genome and clonal hematopoiesis stability contrasts with immune, cfDNA, mitochondrial, and telomere length changes during short duration spaceflight.
Garcia-Medina JS, Sienkiewicz K, Narayanan SA, Overbey EG, Grigorev K, Ryon KA, Burke M, Proszynski J, Tierney B, Schmidt CM, Mencia-Trinchant N, Klotz R, Ortiz V, Foox J, Chin C, Najjar D, Matei I, Chan I, Cruchaga C, Kleinman A, Kim J, Lucaci A, Loy C, Mzava O, De Vlaminck I, Singaraju A, Taylor LE, Schmidt JC, Schmidt MA, Blease K, Moreno J, Boddicker A, Zhao J, Lajoie B, Altomare A, Kruglyak S, Levy S, Yu M, Hassane DC, Bailey SM, Bolton K, Mateus J, Mason CE. Garcia-Medina JS, et al. Among authors: bolton k. Precis Clin Med. 2024 Apr 8;7(1):pbae007. doi: 10.1093/pcmedi/pbae007. eCollection 2024 Mar. Precis Clin Med. 2024. PMID: 38634106 Free PMC article.
ArCH: improving the performance of clonal hematopoiesis variant calling and interpretation.
Chan ICC, Panchot A, Schmidt E, McNulty S, Wiley BJ, Liu J, Turner K, Moukarzel L, Wong WSW, Tran D, Beeler JS, Batchi-Bouyou AL, Machiela MJ, Karyadi DM, Krajacich BJ, Zhao J, Kruglyak S, Lajoie B, Levy S, Patel M, Kantoff PW, Mason CE, Link DC, Druley TE, Stopsack KH, Bolton KL. Chan ICC, et al. Among authors: bolton kl. Bioinformatics. 2024 Mar 29;40(4):btae121. doi: 10.1093/bioinformatics/btae121. Bioinformatics. 2024. PMID: 38485690 Free PMC article.
Clinical and Therapeutic Implications of Clonal Hematopoiesis.
Petrone G, Turker I, Natarajan P, Bolton KL. Petrone G, et al. Among authors: bolton kl. Annu Rev Genomics Hum Genet. 2024 Aug;25(1):329-351. doi: 10.1146/annurev-genom-120722-100409. Annu Rev Genomics Hum Genet. 2024. PMID: 39190914 Review.
Germline predisposition to clonal hematopoiesis.
Liu J, Osman AEG, Bolton K, Godley LA. Liu J, et al. Among authors: bolton k. Leuk Res. 2023 Sep;132:107344. doi: 10.1016/j.leukres.2023.107344. Epub 2023 Jun 19. Leuk Res. 2023. PMID: 37421681 Review.
Unraveling facets of MECOM-associated syndrome: somatic genetic rescue, clonal hematopoiesis, and phenotype expansion.
Venugopal P, Arts P, Fox LC, Simons A, Hiwase DK, Bardy PG, Swift A, Ross DM, van Vulpen LFD, Buijs A, Bolton KL, Getta B, Furlong E, Carter T, Krapels I, Hoeks M, Al Kindy A, Al Kindy F, de Munnik S, Evans P, Frank MSB, Bournazos AM, Cooper ST, Ha TT, Jackson MR, Arriola-Martinez L, Phillips K, Brennan Y, Bakshi M, Ambler K, Gao S, Kassahn KS, Kenyon R, Hung K, Babic M, McGovern A, Rawlings L, Vakulin C, Dejong L, Fathi R, McRae S, Myles N, Ladon D, Jongmans M, Kuiper RP, Poplawski NK, Barbaro P, Blombery P, Brown AL, Hahn CN, Scott HS. Venugopal P, et al. Among authors: bolton kl. Blood Adv. 2024 Jul 9;8(13):3437-3443. doi: 10.1182/bloodadvances.2023012331. Blood Adv. 2024. PMID: 38662475 Free PMC article. No abstract available.
A blueprint for pursuing therapeutic interventions and early phase clinical trials in clonal haematopoiesis.
Haque T, Shastri A, Desai P, Xie Z, Hammond D, King Z, Kishtagari A, Madanat YF, Abaza Y, Silver AJ, Singh A, Borate UM, Heimlich JB, Slosky DA, Bolton KL, Patnaik MS, Bick AG, Verma AK, Jaiswal S, Steensma DP, Savona MR. Haque T, et al. Among authors: bolton kl. Br J Haematol. 2024 Dec 9. doi: 10.1111/bjh.19925. Online ahead of print. Br J Haematol. 2024. PMID: 39653653 Review.
276 results