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Page 1
Endogenous ether lipids differentially promote tumor aggressiveness by regulating the SK3 channel.
Papin M, Fontaine D, Goupille C, Figiel S, Domingo I, Pinault M, Guimaraes C, Guyon N, Cartron PF, Emond P, Lefevre A, Gueguinou M, Crottès D, Jaffrès PA, Ouldamer L, Maheo K, Fromont G, Potier-Cartereau M, Bougnoux P, Chantôme A, Vandier C. Papin M, et al. Among authors: jaffres pa. J Lipid Res. 2024 May;65(5):100544. doi: 10.1016/j.jlr.2024.100544. Epub 2024 Apr 18. J Lipid Res. 2024. PMID: 38642894 Free PMC article.
Pivotal role of the lipid Raft SK3-Orai1 complex in human cancer cell migration and bone metastases.
Chantôme A, Potier-Cartereau M, Clarysse L, Fromont G, Marionneau-Lambot S, Guéguinou M, Pagès JC, Collin C, Oullier T, Girault A, Arbion F, Haelters JP, Jaffrès PA, Pinault M, Besson P, Joulin V, Bougnoux P, Vandier C. Chantôme A, et al. Among authors: jaffres pa. Cancer Res. 2013 Aug 1;73(15):4852-61. doi: 10.1158/0008-5472.CAN-12-4572. Epub 2013 Jun 17. Cancer Res. 2013. PMID: 23774210
New Disaccharide-Based Ether Lipids as SK3 Ion Channel Inhibitors.
Berthe W, Sevrain CM, Chantôme A, Bouchet AM, Gueguinou M, Fourbon Y, Potier-Cartereau M, Haelters JP, Couthon-Gourvès H, Vandier C, Jaffrès PA. Berthe W, et al. Among authors: jaffres pa. ChemMedChem. 2016 Jul 19;11(14):1531-9. doi: 10.1002/cmdc.201600147. Epub 2016 Jun 9. ChemMedChem. 2016. PMID: 27278812
Alkyl ether lipids, ion channels and lipid raft reorganization in cancer therapy.
Jaffrès PA, Gajate C, Bouchet AM, Couthon-Gourvès H, Chantôme A, Potier-Cartereau M, Besson P, Bougnoux P, Mollinedo F, Vandier C. Jaffrès PA, et al. Pharmacol Ther. 2016 Sep;165:114-31. doi: 10.1016/j.pharmthera.2016.06.003. Epub 2016 Jun 8. Pharmacol Ther. 2016. PMID: 27288726 Review.
SK3/TRPC1/Orai1 complex regulates SOCE-dependent colon cancer cell migration: a novel opportunity to modulate anti-EGFR mAb action by the alkyl-lipid Ohmline.
Guéguinou M, Harnois T, Crottes D, Uguen A, Deliot N, Gambade A, Chantôme A, Haelters JP, Jaffrès PA, Jourdan ML, Weber G, Soriani O, Bougnoux P, Mignen O, Bourmeyster N, Constantin B, Lecomte T, Vandier C, Potier-Cartereau M. Guéguinou M, et al. Among authors: jaffres pa. Oncotarget. 2016 Jun 14;7(24):36168-36184. doi: 10.18632/oncotarget.8786. Oncotarget. 2016. PMID: 27102434 Free PMC article.
Lipidic synthetic alkaloids as SK3 channel modulators. Synthesis and biological evaluation of 2-substituted tetrahydropyridine derivatives with potential anti-metastatic activity.
Kouba S, Braire J, Félix R, Chantôme A, Jaffrès PA, Lebreton J, Dubreuil D, Pipelier M, Zhang X, Trebak M, Vandier C, Mathé-Allainmat M, Potier-Cartereau M. Kouba S, et al. Among authors: jaffres pa. Eur J Med Chem. 2020 Jan 15;186:111854. doi: 10.1016/j.ejmech.2019.111854. Epub 2019 Nov 9. Eur J Med Chem. 2020. PMID: 31753515
Synthetic alkyl-ether-lipid promotes TRPV2 channel trafficking trough PI3K/Akt-girdin axis in cancer cells and increases mammary tumour volume.
Guéguinou M, Felix R, Marionneau-Lambot S, Oullier T, Penna A, Kouba S, Gambade A, Fourbon Y, Ternant D, Arnoult C, Simon G, Bouchet AM, Chantôme A, Harnois T, Haelters JP, Jaffrès PA, Weber G, Bougnoux P, Carreaux F, Mignen O, Vandier C, Potier-Cartereau M. Guéguinou M, et al. Among authors: jaffres pa. Cell Calcium. 2021 Jun 12;97:102435. doi: 10.1016/j.ceca.2021.102435. Online ahead of print. Cell Calcium. 2021. PMID: 34167050
83 results