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Essential and virulence-related protein interactions of pathogens revealed through deep learning.
Humphreys IR, Zhang J, Baek M, Wang Y, Krishnakumar A, Pei J, Anishchenko I, Tower CA, Jackson BA, Warrier T, Hung DT, Peterson SB, Mougous JD, Cong Q, Baker D. Humphreys IR, et al. Among authors: wang y. bioRxiv [Preprint]. 2024 Apr 12:2024.04.12.589144. doi: 10.1101/2024.04.12.589144. bioRxiv. 2024. Update in: Nat Microbiol. 2024 Oct;9(10):2642-2652. doi: 10.1038/s41564-024-01791-x PMID: 38645026 Free PMC article. Updated. Preprint.
Discovery of a glutathione utilization pathway in Francisella that shows functional divergence between environmental and pathogenic species.
Wang Y, Ledvina HE, Tower CA, Kambarev S, Liu E, Charity JC, Kreuk LSM, Tang Q, Chen Q, Gallagher LA, Radey MC, Rerolle GF, Li Y, Penewit KM, Turkarslan S, Skerrett SJ, Salipante SJ, Baliga NS, Woodward JJ, Dove SL, Peterson SB, Celli J, Mougous JD. Wang Y, et al. Cell Host Microbe. 2023 Aug 9;31(8):1359-1370.e7. doi: 10.1016/j.chom.2023.06.010. Epub 2023 Jul 14. Cell Host Microbe. 2023. PMID: 37453420 Free PMC article.
Streptomyces umbrella toxin particles block hyphal growth of competing species.
Zhao Q, Bertolli S, Park YJ, Tan Y, Cutler KJ, Srinivas P, Asfahl KL, Fonesca-García C, Gallagher LA, Li Y, Wang Y, Coleman-Derr D, DiMaio F, Zhang D, Peterson SB, Veesler D, Mougous JD. Zhao Q, et al. Among authors: wang y. Nature. 2024 May;629(8010):165-173. doi: 10.1038/s41586-024-07298-z. Epub 2024 Apr 17. Nature. 2024. PMID: 38632398 Free PMC article.
295,913 results
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