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Transcription factor Nrf1 regulates proteotoxic stress-induced autophagy.
Ward MA, Vangala JR, Kamber Kaya HE, Byers HA, Hosseini N, Diaz A, Cuervo AM, Kaushik S, Radhakrishnan SK. Ward MA, et al. Among authors: diaz a. J Cell Biol. 2024 Jun 3;223(6):e202306150. doi: 10.1083/jcb.202306150. Epub 2024 Apr 24. J Cell Biol. 2024. PMID: 38656405 Free PMC article.
Lysosomal mTORC2/PHLPP1/Akt Regulate Chaperone-Mediated Autophagy.
Arias E, Koga H, Diaz A, Mocholi E, Patel B, Cuervo AM. Arias E, et al. Among authors: diaz a. Mol Cell. 2015 Jul 16;59(2):270-84. doi: 10.1016/j.molcel.2015.05.030. Epub 2015 Jun 25. Mol Cell. 2015. PMID: 26118642 Free PMC article.
Humanin is an endogenous activator of chaperone-mediated autophagy.
Gong Z, Tasset I, Diaz A, Anguiano J, Tas E, Cui L, Kuliawat R, Liu H, Kühn B, Cuervo AM, Muzumdar R. Gong Z, et al. Among authors: diaz a. J Cell Biol. 2018 Feb 5;217(2):635-647. doi: 10.1083/jcb.201606095. Epub 2017 Nov 29. J Cell Biol. 2018. PMID: 29187525 Free PMC article.
Sarcosine Is Uniquely Modulated by Aging and Dietary Restriction in Rodents and Humans.
Walters RO, Arias E, Diaz A, Burgos ES, Guan F, Tiano S, Mao K, Green CL, Qiu Y, Shah H, Wang D, Hudgins AD, Tabrizian T, Tosti V, Shechter D, Fontana L, Kurland IJ, Barzilai N, Cuervo AM, Promislow DEL, Huffman DM. Walters RO, et al. Among authors: diaz a. Cell Rep. 2018 Oct 16;25(3):663-676.e6. doi: 10.1016/j.celrep.2018.09.065. Cell Rep. 2018. PMID: 30332646 Free PMC article.
Rare variants in the neuronal ceroid lipofuscinosis gene MFSD8 are candidate risk factors for frontotemporal dementia.
Geier EG, Bourdenx M, Storm NJ, Cochran JN, Sirkis DW, Hwang JH, Bonham LW, Ramos EM, Diaz A, Van Berlo V, Dokuru D, Nana AL, Karydas A, Balestra ME, Huang Y, Russo SP, Spina S, Grinberg LT, Seeley WW, Myers RM, Miller BL, Coppola G, Lee SE, Cuervo AM, Yokoyama JS. Geier EG, et al. Among authors: diaz a. Acta Neuropathol. 2019 Jan;137(1):71-88. doi: 10.1007/s00401-018-1925-9. Epub 2018 Oct 31. Acta Neuropathol. 2019. PMID: 30382371 Free PMC article.
A farnesyltransferase inhibitor activates lysosomes and reduces tau pathology in mice with tauopathy.
Hernandez I, Luna G, Rauch JN, Reis SA, Giroux M, Karch CM, Boctor D, Sibih YE, Storm NJ, Diaz A, Kaushik S, Zekanowski C, Kang AA, Hinman CR, Cerovac V, Guzman E, Zhou H, Haggarty SJ, Goate AM, Fisher SK, Cuervo AM, Kosik KS. Hernandez I, et al. Among authors: diaz a. Sci Transl Med. 2019 Mar 27;11(485):eaat3005. doi: 10.1126/scitranslmed.aat3005. Sci Transl Med. 2019. PMID: 30918111 Free PMC article.
Proteome-wide analysis of chaperone-mediated autophagy targeting motifs.
Kirchner P, Bourdenx M, Madrigal-Matute J, Tiano S, Diaz A, Bartholdy BA, Will B, Cuervo AM. Kirchner P, et al. Among authors: diaz a. PLoS Biol. 2019 May 31;17(5):e3000301. doi: 10.1371/journal.pbio.3000301. eCollection 2019 May. PLoS Biol. 2019. PMID: 31150375 Free PMC article.
3,260 results