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Bridging the Gap: Multi-Omics Profiling of Brain Tissue in Alzheimer's Disease and Older Controls in Multi-Ethnic Populations.
Reddy JS, Heath L, Vander Linden A, Allen M, de Paiva Lopes K, Seifar F, Wang E, Ma Y, Poehlman WL, Quicksall ZS, Runnels A, Wang Y, Duong DM, Yin L, Xu K, Modeste ES, Shantaraman A, Dammer EB, Ping L, Oatman SR, Scanlan J, Ho C, Carrasquillo MM, Atik M, Yepez G, Mitchell AO, Nguyen TT, Chen X, Marquez DX, Reddy H, Xiao H, Seshadri S, Mayeux R, Prokop S, Lee EB, Serrano GE, Beach TG, Teich AF, Haroutunian V, Fox EJ, Gearing M, Wingo A, Wingo T, Lah JJ, Levey AI, Dickson DW, Barnes LL, De Jager P, Zhang B, Bennett D, Seyfried NT, Greenwood AK, Ertekin-Taner N. Reddy JS, et al. Among authors: serrano ge. bioRxiv [Preprint]. 2024 Apr 20:2024.04.16.589592. doi: 10.1101/2024.04.16.589592. bioRxiv. 2024. Update in: Alzheimers Dement. 2024 Oct;20(10):7174-7192. doi: 10.1002/alz.14208 PMID: 38659743 Free PMC article. Updated. Preprint.
Impaired hepatic amyloid-beta degradation in Alzheimer's disease.
Maarouf CL, Walker JE, Sue LI, Dugger BN, Beach TG, Serrano GE. Maarouf CL, et al. Among authors: serrano ge. PLoS One. 2018 Sep 7;13(9):e0203659. doi: 10.1371/journal.pone.0203659. eCollection 2018. PLoS One. 2018. PMID: 30192871 Free PMC article.
Large-scale deep multi-layer analysis of Alzheimer's disease brain reveals strong proteomic disease-related changes not observed at the RNA level.
Johnson ECB, Carter EK, Dammer EB, Duong DM, Gerasimov ES, Liu Y, Liu J, Betarbet R, Ping L, Yin L, Serrano GE, Beach TG, Peng J, De Jager PL, Haroutunian V, Zhang B, Gaiteri C, Bennett DA, Gearing M, Wingo TS, Wingo AP, Lah JJ, Levey AI, Seyfried NT. Johnson ECB, et al. Among authors: serrano ge. Nat Neurosci. 2022 Feb;25(2):213-225. doi: 10.1038/s41593-021-00999-y. Epub 2022 Feb 3. Nat Neurosci. 2022. PMID: 35115731 Free PMC article.
Low circulating choline, a modifiable dietary factor, is associated with the pathological progression and metabolome dysfunction in Alzheimer's disease.
Judd JM, Jasbi P, Winslow W, Serrano GE, Beach TG, Klein-Seetharaman J, Velazquez R. Judd JM, et al. Among authors: serrano ge. bioRxiv [Preprint]. 2023 May 8:2023.05.06.539713. doi: 10.1101/2023.05.06.539713. bioRxiv. 2023. Update in: Acta Neuropathol. 2023 Oct;146(4):565-583. doi: 10.1007/s00401-023-02616-7 PMID: 37214864 Free PMC article. Updated. Preprint.
232 results