Love MI - Search Results

1

Machine learning methods for predicting guide RNA effects in CRISPR epigenome editing experiments.

Mu W, Luo T, Barrera A, Bounds LR, Klann TS, Ter Weele M, Bryois J, Crawford GE, Sullivan PF, Gersbach CA, Love MI, Li Y. Mu W, et al. Among authors: love mi. bioRxiv [Preprint]. 2024 Apr 19:2024.04.18.590188. doi: 10.1101/2024.04.18.590188. bioRxiv. 2024. PMID: 38659894 Free PMC article. Preprint.

2

Cross-site reproducibility of human cortical organoids reveals consistent cell type composition and architecture.

Glass MR, Waxman EA, Yamashita S, Lafferty M, Beltran AA, Farah T, Patel NK, Singla R, Matoba N, Ahmed S, Srivastava M, Drake E, Davis LT, Yeturi M, Sun K, Love MI, Hashimoto-Torii K, French DL, Stein JL. Glass MR, et al. Among authors: love mi. Stem Cell Reports. 2024 Sep 10;19(9):1351-1367. doi: 10.1016/j.stemcr.2024.07.008. Epub 2024 Aug 22. Stem Cell Reports. 2024. PMID: 39178845 Free PMC article.

3

Genetics of cell-type-specific post-transcriptional gene regulation during human neurogenesis.

Aygün N, Vuong C, Krupa O, Mory J, Le BD, Valone JM, Liang D, Shafie B, Zhang P, Salinda A, Wen C, Gandal MJ, Love MI, de la Torre-Ubieta L, Stein JL. Aygün N, et al. Among authors: love mi. Am J Hum Genet. 2024 Sep 5;111(9):1877-1898. doi: 10.1016/j.ajhg.2024.07.015. Epub 2024 Aug 20. Am J Hum Genet. 2024. PMID: 39168119

4

Extensive co-regulation of neighboring genes complicates the use of eQTLs in target gene prioritization.

Tambets R, Kolde A, Kolberg P, Love MI, Alasoo K. Tambets R, et al. Among authors: love mi. HGG Adv. 2024 Oct 10;5(4):100348. doi: 10.1016/j.xhgg.2024.100348. Epub 2024 Aug 29. HGG Adv. 2024. PMID: 39210598 Free PMC article.

5

Response eQTLs, chromatin accessibility, and 3D chromatin structure in chondrocytes provide mechanistic insight into osteoarthritis risk.

Kramer NE, Byun S, Coryell P, D'Costa S, Thulson E, Kim H, Parkus SM, Bond ML, Klein ER, Shine J, Chubinskaya S, Love MI, Mohlke KL, Diekman BO, Loeser RF, Phanstiel DH. Kramer NE, et al. Among authors: love mi. Cell Genom. 2025 Jan 8;5(1):100738. doi: 10.1016/j.xgen.2024.100738. Cell Genom. 2025. PMID: 39788104

6

Gaussian processes for time series with lead-lag effects with applications to biology data.

Mu W, Chen J, Davis ES, Reed K, Phanstiel D, Love MI, Li D. Mu W, et al. Among authors: love mi. Biometrics. 2025 Jan 7;81(1):ujae156. doi: 10.1093/biomtc/ujae156. Biometrics. 2025. PMID: 39775854

7

Adipose tissue eQTL meta-analysis highlights the contribution of allelic heterogeneity to gene expression regulation and cardiometabolic traits.

Brotman SM, El-Sayed Moustafa JS, Guan L, Broadaway KA, Wang D, Jackson AU, Welch R, Currin KW, Tomlinson M, Vadlamudi S, Stringham HM, Roberts AL, Lakka TA, Oravilahti A, Fernandes Silva L, Narisu N, Erdos MR, Yan T, Bonnycastle LL, Raulerson CK, Raza Y, Yan X, Parker SCJ, Kuusisto J, Pajukanta P, Tuomilehto J, Collins FS, Boehnke M, Love MI, Koistinen HA, Laakso M, Mohlke KL, Small KS, Scott LJ. Brotman SM, et al. Among authors: love mi. Nat Genet. 2025 Jan 2. doi: 10.1038/s41588-024-01982-6. Online ahead of print. Nat Genet. 2025. PMID: 39747594

8

Stimulating Wnt signaling reveals context-dependent genetic effects on gene regulation in primary human neural progenitors.

Matoba N, Le BD, Valone JM, Wolter JM, Mory JT, Liang D, Aygün N, Broadaway KA, Bond ML, Mohlke KL, Zylka MJ, Love MI, Stein JL. Matoba N, et al. Among authors: love mi. Nat Neurosci. 2024 Dec;27(12):2430-2442. doi: 10.1038/s41593-024-01773-6. Epub 2024 Sep 30. Nat Neurosci. 2024. PMID: 39349663

9

Deciphering the impact of genomic variation on function.

IGVF Consortium. IGVF Consortium. Nature. 2024 Sep;633(8028):47-57. doi: 10.1038/s41586-024-07510-0. Epub 2024 Sep 4. Nature. 2024. PMID: 39232149 Review.

10

Liver eQTL meta-analysis illuminates potential molecular mechanisms of cardiometabolic traits.

Broadaway KA, Brotman SM, Rosen JD, Currin KW, Alkhawaja AA, Etheridge AS, Wright F, Gallins P, Jima D, Zhou YH, Love MI, Innocenti F, Mohlke KL. Broadaway KA, et al. Among authors: love mi. Am J Hum Genet. 2024 Sep 5;111(9):1899-1913. doi: 10.1016/j.ajhg.2024.07.017. Epub 2024 Aug 21. Am J Hum Genet. 2024. PMID: 39173627

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